CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007603
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Essential for maintenance of the cell wall protein 1 
Protein Synonyms/Alias
  
Gene Name
 EMW1 
Gene Synonyms/Alias
 YNL313C; N0364 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
604NAKNSLAKYYFNPPPubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Required for the maintenance of the cell wall integrity. 
Sequence Annotation
 REPEAT 510 544 TPR 1.
 REPEAT 563 596 TPR 2.
 REPEAT 603 636 TPR 3.
 REPEAT 637 670 TPR 4.
 REPEAT 671 704 TPR 5.
 REPEAT 706 739 TPR 6.  
Keyword
 Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Nucleus; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 904 AA 
Protein Sequence
METLLHAKLL LSAEVESLKS GSFDQTYVKK AEHIISGESY QLVQQFVDKF KGKISISGEI 60
STSSVIAALN DFLNVEVFKM GQENEMLFLA IALLQTFIQN NYTGPAARLK AISGLFGKTG 120
IEIGAVNTAL SRSLAIMGQP AYEFMDDPLY LVLSLLLLER ITGQKSLFDV TPDQEIPLPI 180
ISAESTPGLL AVAYWWWARA LLTQLSLIPE PSGFQASVAS AIYQSADLAY AITKELPESI 240
HEDFKRELCA MYYLENVKCS LAINTEHLCL PSLTRAKKIT NFEFVMTGAR ATRTKYQQKA 300
HAGLIILAKS FTFQNFALRT TSATPETFAL ESDLLLEKPH FESIADEPLD EQIYSKRQKV 360
DLNEGYEEDK LLPLALRQEN IPKLLLDLNP NDQPTLSDYD NIQLLLRLYT IKNTTPAKDP 420
LVEEELTALL SRILYQNGDK NWSIFARSLW ERSIIETTKA KTIERGLLQM QSLVEELDLK 480
IKSKLVPSSS EINVASRLSY IHQLPFIPRW QLDATLAEKY MSLGILKSAV EIYERLGMAC 540
ETALCYAAVG DEKKAEEILL QRINENDSDA RAYSILGDIK QDPSLWEKSW EIGKYVNAKN 600
SLAKYYFNPP PKSGAQPNYS ATLKHLNDSL RQYPLSFETW YFYGCVGLQC GKMQIAAEAF 660
TRCVSLDPYH ALSWSNLSAA YTKMDKLKEA YSCLKRAISC DAQKNWKIWE NYMLVAVKLN 720
EWEDVLTACK QLVSIRRDKS GEGSIDLPII EKLVELLVTS EYPEEPQQLS YFQKSCTEFI 780
CNTLPQVITT SARCWRLVAR VELWRKRPWA ALECHEKAYR AISHNPDLEV EEKVWNDTVD 840
ACEDLVAAYE SLGEMEGKYG PGSLVCKDWK YKCRSTIKAL MSKGKGRWDD SPGWDRLVEA 900
RSQI 904 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0031505; P:fungal-type cell wall organization; IMP:SGD. 
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
  
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS