CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041930
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin 3, epithelial, isoform CRA_l 
Protein Synonyms/Alias
 Ankyrin-3 
Gene Name
 Ank3 
Gene Synonyms/Alias
 mCG_14429 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
39ARAGHLEKALDYIKNubiquitination[1]
260TPLHVASKRGNANMVubiquitination[1]
623TPLHIAAKKNQMDIAubiquitination[1]
925EELLVPSKEQHLTFTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1940 AA 
Protein Sequence
MSEEPKEKPA KPAHRKRKGK KSDANASYLR AARAGHLEKA LDYIKNGVDV NICNQNGLNA 60
LHLASKEGHV EVVSELLQRE ANVDAATKKG NTALHIASLA GQAEVVKVLV TNGANVNAQS 120
QNGFTPLYMA AQENHLEVVR FLLDNGASQS LATEDGFTPL AVALQQGHDQ VVSLLLENDT 180
KGKVRLPALH IAARKDDTKA AALLLQNDTN ADVESKSGFT PLHIAAHYGN INVATLLLNR 240
AAAVDFTARN DITPLHVASK RGNANMVKLL LDRGAKIDAK TRDGLTPLHC GARSGHEQVV 300
EMLLDRSAPI LSKTKNGLSP LHMATQGDHL NCVQLLLQHN VPVDDVTNDY LTALHVAAHC 360
GHYKVAKVLL DKKASPNAKA LNGFTPLHIA CKKNRIRVME LLLKHGASIQ AVTESGLTPI 420
HVAAFMGHVN IVSQLMHHGA SPNTTNVRGE TALHMAARSG QAEVVRYLVQ DGAQVEAKAK 480
DDQTPLHISA RLGKADIVQQ LLQQGASPNA ATTSGYTPLH LAAREGHEDV AAFLLDHGAS 540
LSITTKKGFT PLHVAAKYGK LEVASLLLQK SASPDAAGKS GLTPLHVAAH YDNQKVALLL 600
LDQGASPHAA AKNGYTPLHI AAKKNQMDIA TSLLEYGADA NAVTRQGIAS VHLAAQEGHV 660
DMVSLLLSRN ANVNLSNKSG LTPLHLAAQE DRVNVAEVLV NQGAHVDAQT KMGYTPLHVG 720
CHYGNIKIVN FLLQHSAKVN AKTKNGYTAL HQAAQQGHTH IINVLLQNNA SPNELTVNGN 780
TALAIARRLG YISVVDTLKV VTEEIMTTTT ITEKHKMNVP ETMNEVLDMS DDEGDKCTWF 840
KIPKVQEVLV KSEDAITGDT DKYLGPQDLK ELGDDSLPAE GYVGFSLGAR SASLRSFSSD 900
RSYTLNRSSY ARDSMMIEEL LVPSKEQHLT FTREFDSDSL RHYSWAADTL DNVNLVSSPV 960
HSGFLVSFMV DARGGSMRGS RHHGMRIIIP PRKCTAPTRI TCRLVKRHKL ANPPPMVEGE 1020
GLASRLVEMG PAGAQFLGPV IVEIPHFGSM RGKERELIVL RSENGETWKE HQFDSKNEDL 1080
AELLNGMDEE LDSPEELGTK RICRIITKDF PQYFAVVSRI KQESNQIGPE GGILSSTTVP 1140
LVQASFPEGA LTKRIRVGLQ AQPVPEETVK KILGNKATFS PIVTVEPRRR KFHKPITMTI 1200
PVPPPSGEGV SNGYKGDATP NLRLLCSITG GTSPAQWEDI TGTTPLTFIK DCVSFTTNVS 1260
ARFWLADCHQ VLETVGLASQ LYRELICVPY MAKFVVFAKT NDPVESSLRC FCMTDDRVDK 1320
TLEQQENFEE VARSKDIEVL EGKPIYVDCY GNLAPLTKGG QQLVFNFYSF KENRLPFSIK 1380
IRDTSQEPCG RLSFLKEPKT TKGLPQTAVC NLNITLPAHK KAEKADRRQS FASLALRKRY 1440
SYLTEPSMSP QSPCERTDIR MAIVADHLGL SWTELARELN FSVDEINQIR VENPNSLISQ 1500
SFMLLKKWVT RDGKNATTDA LTSVLTKINR IDIVTLLEGP IFDYGNISGT RSFADENNVF 1560
HDPVDGHPSF QVELETPMGL YCTPPNPFQQ DDHFSDISSI ESPFRTPSRL SDGLVPSQGN 1620
IEHPTGGPPV VTAEDTSLED SKMDDSVTVT DPADPLDVDE SQLKDLCQSE CAQCWASVPG 1680
IPNDGRQAEP LRPQTRKVGM SSEQQEKGKS GPDEEVTEDK VKSLFEDIQL EEVEAEEMTE 1740
DQGQAMLNRV QRAELAMSSL AGWQNETPSG SLESPAQARR LTGGLLDRLD DSSDQARDSI 1800
TSYLTGEPGK IEANGNHTAE VIPEAKAKPY FPESQNDIGK QSIKENLKPK THGCGRTEEP 1860
VSPLTAYQKS LEETSKLVIE DAPKPCVPVG MKKMTRTTAD GKARLNLQEE EGSTRSEPKQ 1920
GEGYKVKTKK EIRNVEKKTH 1940 
Gene Ontology
 GO:0043194; C:axon initial segment; IDA:MGI.
 GO:0014704; C:intercalated disc; IDA:MGI.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0033270; C:paranode region of axon; IDA:MGI.
 GO:0045202; C:synapse; IDA:MGI.
 GO:0007411; P:axon guidance; IMP:MGI.
 GO:0007165; P:signal transduction; IEA:InterPro.
 GO:0050808; P:synapse organization; IMP:MGI. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR011029; DEATH-like_dom.
 IPR000488; Death_domain.
 IPR000906; ZU5. 
Pfam
 PF00023; Ank
 PF12796; Ank_2
 PF00531; Death
 PF00791; ZU5 
SMART
 SM00248; ANK
 SM00005; DEATH
 SM00218; ZU5 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50017; DEATH_DOMAIN
 PS51145; ZU5 
PRINTS
 PR01415; ANKYRIN.