CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021926
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Elongation factor 1-gamma 
Protein Synonyms/Alias
 EF-1-gamma; eEF-1B gamma 
Gene Name
 Ef1gamma 
Gene Synonyms/Alias
 Ef1g; CG11901 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
36VKVADNFKFGETNKSacetylation[1]
42FKFGETNKSAEFLKKacetylation[1]
48NKSAEFLKKFPGGKVacetylation[1]
201KQVQAVVKDYKLCEKacetylation[1]
215KALVFDPKKYAEFQAacetylation[1]
428GRKFNQGKIFK****acetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Probably plays a role in anchoring the complex to other cellular components. 
Sequence Annotation
 DOMAIN 2 84 GST N-terminal.
 DOMAIN 86 212 GST C-terminal.
 DOMAIN 272 431 EF-1-gamma C-terminal.  
Keyword
 Complete proteome; Elongation factor; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MVKGTLYTYP ENFRAYKALI AAQYSGAQVK VADNFKFGET NKSAEFLKKF PGGKVPAFET 60
AEGQYLSESN AIAYLLANEQ LRGGKCPFVQ AQVQQWISFA DNEIVPASCA WVFPLLGILP 120
QQKNSTAKQE AEAVLQQLNQ KLQDATFLAG ERITLADIVV FSSLLHLYEY VLEPSVRSAF 180
GNVNRWFVTI LNQKQVQAVV KDYKLCEKAL VFDPKKYAEF QAKTGAAKPQ QQAQQQKQEK 240
KPKEKKEAPK KAAEPAEELD AADEALAAEP KSKDPFDALP KGTFNFDDFK RVYSNEDEAK 300
SIPYFFDKFD AENYSIWFGE YKYNEELSKV FMSCNLITGM FQRLDKMRKA AFASVCLFGE 360
DGNSTISGIW VWRGQDLAFT LSPDWQIDYE VYDWKKLDAK SEETKKLVTQ YFSWSGTDKD 420
GRKFNQGKIF K 431 
Gene Ontology
 GO:0005853; C:eukaryotic translation elongation factor 1 complex; ISS:FlyBase.
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0003746; F:translation elongation factor activity; ISS:FlyBase.
 GO:0035071; P:salivary gland cell autophagic cell death; IEP:FlyBase. 
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR012336; Thioredoxin-like_fold.
 IPR001662; Transl_elong_EF1_G_con. 
Pfam
 PF00647; EF1G
 PF00043; GST_C
 PF02798; GST_N 
SMART
  
PROSITE
 PS50040; EF1G_C
 PS50405; GST_CTER
 PS50404; GST_NTER 
PRINTS