CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042217
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 LOC100735563 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
454GEVLLVRKELNKMLEacetylation[1]
458LVRKELNKMLEGKSKacetylation[1]
633EFRKYLEKPITMLL*acetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Lipoyl; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 639 AA 
Protein Sequence
MWRVCARRAH RAAPEAGLGA RWTALREGPG APRVSLRSSR APARSNSTTT PGYGGVRALG 60
GWSASSGAAP RNRLLLQLLG LPGRRCYSLP PHQKVPLPSL SPTMQAGTIA RWINEGDLIA 120
EVETDKATVG FESLEECYMA KILVAEGTRD VPVGAVICIT VGKPEDIEAF KNYTLDSSAA 180
PTPQAAPAPT STAAASPPAP SPQAPGSSYP PHMQVLLPAL SPTMTMGTVQ RWGEKLSEGD 240
LLAEIETDKA TIGFEVQEEG YLAKILVPEG TRDVPLGTPL CIIVEKEADI AAFADYRPTE 300
VTDLKPQAPP AVPPLVAAVP PSPQPVSPAP SGAPGVPATP AGPKGRIFVS PLAKKLAAEK 360
GIDLTQVKGT GPDGRIIKKD IDSFVPPKAA PAPAAAVPPP SPGVAPVPTG VFTDVPVSNI 420
RRVIAQRLMQ SKQTIPHYYL SIDVNMGEVL LVRKELNKML EGKSKISVND FIIKASALAC 480
LKVPEANSSW MDTVIRQNHV VDISVAVSTA AGLITPIVFN AHIKGLETIA NDVVSLATKA 540
REGKLQPHEF QGGTFTISNL GMFGIKNFSA IINPPQACIL AIGASEDKLV PADNEKGFDV 600
ASMMSVTLSC DHRVVDGAVG AQWLAEFRKY LEKPITMLL 639 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
 GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:InterPro.
 GO:0006090; P:pyruvate metabolic process; IEA:InterPro. 
Interpro
 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR001078; 2-oxoacid_DH_actylTfrase.
 IPR000089; Biotin_lipoyl.
 IPR023213; CAT-like_dom.
 IPR004167; E3-bd.
 IPR006257; LAT1.
 IPR011053; Single_hybrid_motif. 
Pfam
 PF00198; 2-oxoacid_dh
 PF00364; Biotin_lipoyl
 PF02817; E3_binding 
SMART
  
PROSITE
 PS50968; BIOTINYL_LIPOYL
 PS00189; LIPOYL 
PRINTS