CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017550
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 THAP domain-containing protein 8 
Protein Synonyms/Alias
  
Gene Name
 THAP8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
28NRPVSFYKFPLKDGPubiquitination[1]
32SFYKFPLKDGPRLQAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 ZN_FING 1 85 THAP-type.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Polymorphism; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 274 AA 
Protein Sequence
MPKYCRAPNC SNTAGRLGAD NRPVSFYKFP LKDGPRLQAW LQHMGCEHWV PSCHQHLCSE 60
HFTPSCFQWR WGVRYLRPDA VPSIFSRGPP AKSQRRTRST QKPVSPPPPL QKNTPLPQSP 120
AIPVSGPVRL VVLGPTSGSP KTVATMLLTP LAPAPTPERS QPEVPAQQAQ TGLGPVLGAL 180
QRRVRRLQRC QERHQAQLQA LERLAQQLHG ESLLARARRG LQRLTTAQTL GPEESQTFTI 240
ICGGPDIAMV LAQDPAPATV DAKPELLDTR IPSA 274 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR026522; THAP8.
 IPR006612; Znf_C2CH. 
Pfam
 PF05485; THAP 
SMART
 SM00692; DM3
 SM00980; THAP 
PROSITE
 PS50950; ZF_THAP 
PRINTS