CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037238
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine--tRNA ligase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 SARS2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
195VLHMVGDKPVFSFQPubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 518 AA 
Protein Sequence
MEGVWQELLD SAQIEICVAD WWGARENCGC VYQLRVRLLD VYEKEVVKFS ASPDPVLQWT 60
ERGCRQVSHV FTNFGKGIRY VSFEQYGRDI STWQELRQLQ EQIRSLEEEK AAVTEAVRAL 120
LANQDSGEVQ QDPKYQGLRA RGREIRKELV HLYPREAQLE EQFYLQALKL PNQTHPDVPV 180
GDESQARVLH MVGDKPVFSF QPRGHLEIGE KLDIIRQKRL SHVSGHRSYY LRGAGALLQH 240
GLVNFTFNKL LRRGFTPMTV PDLLRGAVFE GCGMTPNANP SQIYNIDPAR FKDLNLAGTA 300
EVGLAGYFMD HTVAFRDLPV RMVCSSTCYR AETNTGQEPR GLYRVHHFTK VEMFGVTGPG 360
LEQSSQLLEE FLSLQMEILT ELGLHFRVLD MPTQELGLPA YRKFDIEAWM PGRGRFGEVT 420
SASNCTDFQS RRLHIMFQTE AGELQFAHTV NATACAVPRL LIALLESNQQ KDGSVLVPPA 480
LQSYLGTDRI TAPTHVPLQY IGPNQPRKPG LPGQPAVS 518 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004828; F:serine-tRNA ligase activity; IEA:InterPro.
 GO:0030163; P:protein catabolic process; IEA:InterPro.
 GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR002314; aa-tRNA-synt_IIb_cons-dom.
 IPR006195; aa-tRNA-synth_II.
 IPR007397; F-box-assoc_dom.
 IPR008979; Galactose-bd-like.
 IPR002317; Ser-tRNA-ligase_type_1.
 IPR015866; Ser-tRNA-synth_1_N.
 IPR010978; tRNA-bd_arm. 
Pfam
 PF04300; FBA
 PF00587; tRNA-synt_2b 
SMART
  
PROSITE
 PS50862; AA_TRNA_LIGASE_II
 PS51114; FBA 
PRINTS
 PR00981; TRNASYNTHSER.