| Tag | Content |
|---|
| CPLM ID | CPLM-016268 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Liprin-beta-1 |
Protein Synonyms/Alias | Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF-interacting protein-binding protein 1; hSGT2 |
Gene Name | PPFIBP1 |
Gene Synonyms/Alias | KIAA1230 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 609 | DMSEPEFKRGGTRAT | ubiquitination | [1] | | 640 | DLDMPFAKWTKEQVC | ubiquitination | [1] | | 731 | DIGLPQYKTQFDEGR | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. |
Sequence Annotation | DOMAIN 647 711 SAM 1.
DOMAIN 719 782 SAM 2.
DOMAIN 804 876 SAM 3.
MOD_RES 37 37 Phosphoserine.
MOD_RES 39 39 Phosphothreonine.
MOD_RES 40 40 Phosphoserine.
MOD_RES 309 309 N6-acetyllysine.
MOD_RES 322 322 N6-acetyllysine.
MOD_RES 466 466 Phosphoserine.
MOD_RES 579 579 Phosphoserine.
MOD_RES 601 601 Phosphoserine.
MOD_RES 999 999 Phosphoserine.
MOD_RES 1001 1001 Phosphoserine.
MOD_RES 1003 1003 Phosphoserine.
MOD_RES 1005 1005 Phosphothreonine. |
Keyword | Acetylation; Alternative splicing; Coiled coil; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1011 AA |
Protein Sequence | MMSDASDMLA AALEQMDGII AGSKALEYSN GIFDCQSPTS PFMGSLRALH LVEDLRGLLE 60
MMETDEKEGL RCQIPDSTAE TLVEWLQSQM TNGHLPGNGD VYQERLARLE NDKESLVLQV 120
SVLTDQVEAQ GEKIRDLEFC LEEHREKVNA TEEMLQQELL SRTSLETQKL DLMAEISNLK 180
LKLTAVEKDR LDYEDKFRDT EGLIQEINDL RLKVSEMDSE RLQYEKKLKS TKDELASLKE 240
QLEEKESEVK RLQEKLVCKM KGEGVEIVDR DENFKKKLKE KNIEVQKMKK AVESLMAANE 300
EKDRKIEDLR QCLNRYKKMQ DTVVLAQGKK GKDGEYEELL NSSSISSLLD AQGFSDLEKS 360
PSPTPVMGSP SCDPFNTSVP EEFHTTILQV SIPSLLPATV SMETSEKSKL TPKPETSFEE 420
NDGNIILGAT VDTQLCDKLL TSSLQKSSSL GNLKKETSDG EKETIQKTSE DRAPAESRPF 480
GTLPPRPPGQ DTSMDDNPFG TRKVRSSFGR GFFKIKSNKR TASAPNLDRK RSASAPTLAE 540
TEKETAEHLD LAGASSRPKD SQRNSPFQIP PPSPDSKKKS RGIMKLFGKL RRSQSTTFNP 600
DDMSEPEFKR GGTRATAGPR LGWSRDLGQS NSDLDMPFAK WTKEQVCNWL MEQGLGSYLN 660
SGKHWIASGQ TLLQASQQDL EKELGIKHSL HRKKLQLALQ ALGSEEETNH GKLDFNWVTR 720
WLDDIGLPQY KTQFDEGRVD GRMLHYMTVD DLLSLKVVSV LHHLSIKRAI QVLRINNFEP 780
NCLRRRPSDE NTIAPSEVQK WTNHRVMEWL RSVDLAEYAP NLRGSGVHGG LMVLEPRFNV 840
ETMAQLLNIP PNKTLLRRHL ATHFNLLIGA EAQHQKRDAM ELPDYVLLTA TAKVKPKKLA 900
FSNFGNLRKK KQEDGEEYVC PMELGQASGS ASKKGFKPGL DMRLYEEDDL DRLEQMEDSE 960
GTVRQIGAFS EGINNLTHML KEDDMFKDFA ARSPSASITD EDSNV 1005 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |