CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035649
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Propionyl-CoA carboxylase alpha chain, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Pcca 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
74PKEKTFDKILIANRGacetylation[1]
141DAIMEAIKKTGAQAVacetylation[1]
159YGFLSENKEFAKCLAacetylation[1]
335VALAKAVKYSSAGTVacetylation[1]
414VYAEDPYKSFGLPSIacetylation[1]
471SDRAEALKRMEDALDacetylation[1]
503IINTRFVKGDISTKFacetylation[1]
509VKGDISTKFLSDVYPacetylation[1]
565VIRPDVAKWELSVKLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Biotin; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 640 AA 
Protein Sequence
MAGLWVRTVA LLAARRHWRR SSQQLLWTLK HSGRQRHHFV YTLKRAPVYS QQCLVVSRSL 60
SSVEYEPKEK TFDKILIANR GEIACRVIKT CRKMGIRTVA IHSDVDASSV HVKMADEAVC 120
VGPAPTSKSY LNMDAIMEAI KKTGAQAVHP GYGFLSENKE FAKCLAAECR VLVAPSSSNQ 180
KTLGDSLSSS RVVPHGINVE SHFLPLQDAD EAVRIAREIG YPVMIKASAG GGGKGMRIAW 240
DDEETRDGFR FSSQEAASSF GDDRLLIEKF IDNPRHIEIQ VLGDKHGNAL WLNERECSIQ 300
RRNQKVVEEA PSIFLDPETR RAMGEQAVAL AKAVKYSSAG TVEFLVDSQK NFYFLEMNTR 360
LQVEHPVTEC ITGLDLVQEM ILVAKGYPLR HKQEDIPISG WAVECRVYAE DPYKSFGLPS 420
IGRLSQYQEP IHLPGVRVDS GIQPGXTVCV SGADILGNLV TYGSDRAEAL KRMEDALDSY 480
VIRGVTHNIP LLREVIINTR FVKGDISTKF LSDVYPDGFK GHMLTPSERD QLLAIASSLF 540
VASQLRAQRF QEHSRVPVIR PDVAKWELSV KLHDEDHTVV ASNNGPTFNV EVDGSKLNVT 600
STWNLASPLL SVNVDGTQRT VQCLSRDAGG NMSIQFLGTV 640 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004075; F:biotin carboxylase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR011761; ATP-grasp.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR011764; Biotin_carboxylation_dom.
 IPR005482; Biotin_COase_C.
 IPR005481; CarbamoylP_synth_lsu_N.
 IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
 IPR016185; PreATP-grasp_dom.
 IPR011054; Rudment_hybrid_motif. 
Pfam
 PF02785; Biotin_carb_C
 PF00289; CPSase_L_chain
 PF02786; CPSase_L_D2 
SMART
 SM00878; Biotin_carb_C 
PROSITE
 PS50975; ATP_GRASP
 PS50979; BC
 PS00866; CPSASE_1
 PS00867; CPSASE_2 
PRINTS