CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010337
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Succinylornithine transaminase 
Protein Synonyms/Alias
 SOAT; Carbon starvation protein C; Succinylornithine aminotransferase 
Gene Name
 astC 
Gene Synonyms/Alias
 argM; cstC; ydjW; b1748; JW1737 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
70ALNEQASKFWHTGNGacetylation[1]
89PVLRLAKKLIDATFAacetylation[1]
135KSGIVAFKNAFHGRTacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. 
Sequence Annotation
 MOD_RES 252 252 N6-(pyridoxal phosphate)lysine (By  
Keyword
 3D-structure; Aminotransferase; Arginine metabolism; Complete proteome; Direct protein sequencing; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 406 AA 
Protein Sequence
MSQPITRENF DEWMIPVYAP APFIPVRGEG SRLWDQQGKE YIDFAGGIAV NALGHAHPEL 60
REALNEQASK FWHTGNGYTN EPVLRLAKKL IDATFADRVF FCNSGAEANE AALKLARKFA 120
HDRYGSHKSG IVAFKNAFHG RTLFTVSAGG QPAYSQDFAP LPADIRHAAY NDINSASALI 180
DDSTCAVIVE PIQGEGGVVP ASNAFLQGLR ELCNRHNALL IFDEVQTGVG RTGELYAYMH 240
YGVTPDLLTT AKALGGGFPV GALLATEECA RVMTVGTHGT TYGGNPLASA VAGKVLELIN 300
TPEMLNGVKQ RHDWFVERLN TINHRYGLFS EVRGLGLLIG CVLNADYAGQ AKQISQEAAK 360
AGVMVLIAGG NVVRFAPALN VSEEEVTTGL DRFAAACEHF VSRGSS 406 
Gene Ontology
 GO:0030170; F:pyridoxal phosphate binding; IEA:HAMAP.
 GO:0043825; F:succinylornithine transaminase activity; IDA:EcoliWiki.
 GO:0019544; P:arginine catabolic process to glutamate; IEA:HAMAP.
 GO:0019545; P:arginine catabolic process to succinate; IMP:EcoCyc.
 GO:0006593; P:ornithine catabolic process; IMP:EcoCyc. 
Interpro
 IPR017652; Ac/SucOrn_transaminase_bac.
 IPR005814; Aminotrans_3.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2.
 IPR026330; SOAT.
 IPR004636; Trfase_AcOrn/SuccOrn_fam. 
Pfam
 PF00202; Aminotran_3 
SMART
  
PROSITE
 PS00600; AA_TRANSFER_CLASS_3 
PRINTS