UniProt Accession

 SRLR_ECOLI; P15082; P77030 

Genbank Protein ID

 J02708; X13463; U29579; U00096; AP009048 

Genbank Nucleotide ID

 AAC13415.1; CAA31820.1; AAA69216.1; AAC75749.1; BAA16568.2 

Protein Name

 Glucitol operon repressor 

Protein Synonyms/Alias

  

Gene Name

 srlR 

Gene Synonyms/Alias

 gutR; b2707; JW2676 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
16	AILEYLQKQGKCSVE	acetylation	[1]
60	YGGVVLNKEESDPPI	acetylation	[1]
70	SDPPIDHKTLINTHK	acetylation	[1]
210	ILMADSSKFGRKSPN	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

  

Sequence Annotation

 DOMAIN 3 58 HTH deoR-type.
 DNA_BIND 20 39 H-T-H motif (Potential).  

Keyword

 Complete proteome; DNA-binding; Phosphotransferase system; Reference proteome; Repressor; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 257 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR014036; DeoR_C.
 IPR001034; HTH_DeoR_N.
 IPR018356; Tscrpt_reg_HTH_DeoR_CS.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00455; DeoRC
 PF08220; HTH_DeoR 

SMART

 SM00420; HTH_DEOR 

PROSITE

 PS00894; HTH_DEOR_1
 PS51000; HTH_DEOR_2 

PRINTS