CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027707
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Doublesex and mab-3 related transcription factor 1 
Protein Synonyms/Alias
 Protein Dmrt1 
Gene Name
 Dmrt1 
Gene Synonyms/Alias
 rCG_47376 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
9PNDDAFGKPSAPTEVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 374 AA 
Protein Sequence
MPNDDAFGKP SAPTEVPHAP GAPPQGKAGG YSKATGAMAG AAGGSSAGGS GGASGSGPSG 60
LGSGSKKSPR LPKCARCRNH GYASPLKGHK RFCMWRDCQC KKCSLIAERQ RVMAAQVALR 120
RQQAQEEELG ISHPIPLPSA AELLVKRENS ASNPCLMAES SSSAQPPPAS TPTPTVSEGR 180
MVIQDIPAVT SRGHMENAPD LMSDPAYYSS FYQPSLFPYY NNLYNYPQYS MALSAESSSG 240
DVGNPLGGSP VKNSLRSLPA PYVPAQTGNQ WQMKTSEGRH PVSSQYRMHS YYGPPSYLGQ 300
SMSQIFTFEE GPSYSEAKAS VFSPPSSQDS GLVSLSSSSP MSNESTKGVL ECESASSEPS 360
SYAVNQVLEE DEDE 374 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IEA:Compara.
 GO:0000902; P:cell morphogenesis; IEA:Compara.
 GO:0008354; P:germ cell migration; IEA:Compara.
 GO:0035556; P:intracellular signal transduction; IDA:RGD.
 GO:0002176; P:male germ cell proliferation; IEA:Compara.
 GO:0030238; P:male sex determination; IEA:Compara.
 GO:0046661; P:male sex differentiation; TAS:RGD.
 GO:0045835; P:negative regulation of meiosis; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0045840; P:positive regulation of mitosis; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0060008; P:Sertoli cell differentiation; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:Compara. 
Interpro
 IPR001275; DM_DNA-bd.
 IPR026607; DMRT/dsx/mab-3.
 IPR022114; DMRT1-like. 
Pfam
 PF00751; DM
 PF12374; Dmrt1 
SMART
 SM00301; DM 
PROSITE
 PS40000; DM_1
 PS50809; DM_2 
PRINTS