CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040804
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 181 
Protein Synonyms/Alias
  
Gene Name
 ZNF181 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
292ECGKAFGKQSILNRHubiquitination[1]
537EKPYECIKCGKTFSCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 615 AA 
Protein Sequence
MPQLQYPEGY LAPNRCLVSN CGVNKMSNDE LVGQNHGMEG EACIGGDVTF NDVAIDFTHE 60
EWGWLSSAQR DLYKDVMVQN YENLVSVAGL SVTKPYVITL LEDGKEPWMM EKKLSKGMIP 120
DWESRWENKE LSTKKDNYDE DSPQTVIIEK VVKQSYEFSN SKKNLEYIEK LEGKHGSQVD 180
HFRPAILTSR ESPTADSVYK YNIFRSTFHS KSTLSEPQKI SAEGNSHKYD ILKKNLPKKS 240
VIKNEKVNGG KKLLNSNKSG AAFSQGKSLT LPQTCNREKI YTCSECGKAF GKQSILNRHW 300
RIHTGEKPYE CRECGKTFSH GSSLTRHLIS HSGEKPYKCI ECGKAFSHVS SLTNHQSTHT 360
GEKPYECMNC GKSFSRVSHL IEHLRIHTQE KLYECRICGK AFIHRSSLIH HQKIHTGEKP 420
YECRECGKAF CCSSHLTRHQ RIHTMEKQYE CNKCLKVFSS LSFLVQHQSI HTEEKPFECQ 480
KCRKSFNQLE SLNMHLRNHI RLKPYECSIC GKAFSHRSSL LQHHRIHTGE KPYECIKCGK 540
TFSCSSNLTV HQRIHTGEKP YKCNECGKAF SKGSNLTAHQ RVHNGEKPNS VVSVEKPLDY 600
MNHYTCEKSY RRETV 615 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS