UniProt Accession

 E0CX48_MOUSE; E0CX48 

Genbank Protein ID

 AC119952 

Genbank Nucleotide ID

  

Protein Name

 Gap junction protein 

Protein Synonyms/Alias

  

Gene Name

 Gjb6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
116	GEKRNEFKDLEDIKR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity). 

Sequence Annotation

  

Keyword

 Cell junction; Cell membrane; Complete proteome; Gap junction; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 173 AA 

Protein Sequence

Gene Ontology

 GO:0005922; C:connexon complex; IEA:InterPro.
 GO:0005921; C:gap junction; IDA:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara.
 GO:0007154; P:cell communication; IEA:InterPro.
 GO:0042471; P:ear morphogenesis; IMP:MGI.
 GO:0007605; P:sensory perception of sound; IMP:MGI. 

Interpro

 IPR000500; Connexin.
 IPR017990; Connexin_CS.
 IPR013092; Connexin_N. 

Pfam

 PF00029; Connexin 

SMART

 SM00037; CNX 

PROSITE

 PS00407; CONNEXINS_1 

PRINTS

 PR00206; CONNEXIN.