Tag | Content |
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CPLM ID | CPLM-007110 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peroxisomal targeting signal 2 receptor |
Protein Synonyms/Alias | PTS2 receptor; Peroxin-7; Peroxisome import protein PAS7 |
Gene Name | PEX7 |
Gene Synonyms/Alias | PAS7; PEB1; YDR142C; YD2943.01C; YD9302.18C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
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165 | NAIILKKKSFTGISK | ubiquitination | [1] |
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Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import essential for import of 3-oxoacyl-CoA thiolase (a PTS2-containing protein) into peroxisomes. May direct thiolase to peroxisomes by shuttling between the cytosol and peroxisomal membranes. |
Sequence Annotation | REPEAT 58 89 WD 1. REPEAT 102 133 WD 2. REPEAT 172 203 WD 3. REPEAT 218 249 WD 4. REPEAT 281 312 WD 5. REPEAT 340 372 WD 6. |
Keyword | Complete proteome; Cytoplasm; Peroxisome; Protein transport; Reference proteome; Repeat; Transport; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 375 AA |
Protein Sequence | MLRYHMQGFS GYGVQYSPFF DNRLAVAAGS NFGLVGNGKL FILEIDRSGR IVEVNSFLTQ 60 DCLFDLAWNE SHENQVLVAQ GDGTLRLFDT TFKEFPIAIF KEHEREVFSC NWNLVNRQNF 120 LSSSWDGSIK IWSPLRKQSL MTLTPRPLEI TKMVDPLNAI ILKKKSFTGI SKNRNCVYQA 180 QFSPHDQNLV LSCSGNSYAS LFDIRLPSGK NQNNFLVHSG LEALTCDFNK YRPYVVATGG 240 VDNAIRIWDI RMLNKNESAT IKRTVPGQLH NSSCINEIPN AHGLAIRKVT WSPHHSNILM 300 SASYDMTCRI WRDLSNDGAK ETYKTNSTDA TKGSIFNFTQ HSEFVFGADW SLWGKPGYVA 360 STAWDGNLFV WNGLG 375 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0005777; C:peroxisome; IDA:SGD. GO:0005053; F:peroxisome matrix targeting signal-2 binding; IDA:SGD. GO:0016560; P:protein import into peroxisome matrix, docking; IPI:SGD. |
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