CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000943
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Myelin protein zero-like protein 2 
Protein Synonyms/Alias
 Epithelial V-like antigen 1 
Gene Name
 MPZL2 
Gene Synonyms/Alias
 EVA; EVA1; UNQ606/PRO1192 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
206ERLNQEKKVSVYLEDubiquitination[1]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
 Mediates homophilic cell-cell adhesion. 
Sequence Annotation
 DOMAIN 27 141 Ig-like V-type.
 CARBOHYD 39 39 N-linked (GlcNAc...).
 CARBOHYD 118 118 N-linked (GlcNAc...) (Potential).
 DISULFID 47 123 By similarity.  
Keyword
 Cell adhesion; Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 215 AA 
Protein Sequence
MYGKSSTRAV LLLLGIQLTA LWPIAAVEIY TSRVLEAVNG TDARLKCTFS SFAPVGDALT 60
VTWNFRPLDG GPEQFVFYYH IDPFQPMSGR FKDRVSWDGN PERYDASILL WKLQFDDNGT 120
YTCQVKNPPD VDGVIGEIRL SVVHTVRFSE IHFLALAIGS ACALMIIIVI VVVLFQHYRK 180
KRWAERAHKV VEIKSKEEER LNQEKKVSVY LEDTD 215 
Gene Ontology
 GO:0005856; C:cytoskeleton; TAS:ProtInc.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
 GO:0007156; P:homophilic cell adhesion; TAS:ProtInc.
 GO:0033077; P:T cell differentiation in thymus; IEA:Compara. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013106; Ig_V-set.
 IPR003596; Ig_V-set_subgr.
 IPR000920; Myelin_P0. 
Pfam
 PF07686; V-set 
SMART
 SM00406; IGv 
PROSITE
 PS50835; IG_LIKE 
PRINTS
 PR00213; MYELINP0.