UniProt Accession

 MCM16_YEAST; Q12262; D6W454 

Genbank Protein ID

 Z49219; Z71255; BK006949 

Genbank Nucleotide ID

 CAA89166.1; CAA94993.1; DAA11470.1 

Protein Name

 Central kinetochore subunit MCM16 

Protein Synonyms/Alias

 Minichromosome maintenance protein 16 

Gene Name

 MCM16 

Gene Synonyms/Alias

 YPR046W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
134	KLIELSSKFPKPTIP	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Component of the central kinetochore, which mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. Required for establishing bipolar spindle- microtubule attachments and proper chromosome segregation. 

Sequence Annotation

  

Keyword

 Cell cycle; Cell division; Centromere; Chromosome; Coiled coil; Complete proteome; Kinetochore; Meiosis; Mitosis; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 181 AA 

Protein Sequence

Gene Ontology

 GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0034087; P:establishment of mitotic sister chromatid cohesion; IMP:SGD.
 GO:0007126; P:meiosis; IEA:UniProtKB-KW. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS