| Tag | Content |
|---|
| CPLM ID | CPLM-008124 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Erythrocyte membrane protein band 4.2 |
Protein Synonyms/Alias | Erythrocyte protein 4.2; P4.2 |
Gene Name | Epb42 |
Gene Synonyms/Alias | Epb4.2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 200 | LKLLSMDKQVKDWNQ | ubiquitination | [1] | | 223 | GALLHALKKKSVLPI | ubiquitination | [1] | | 225 | LLHALKKKSVLPISQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Probably plays an important role in the regulation of erythrocyte shape and mechanical properties. |
Sequence Annotation | REGION 31 39 Band 3 binding (By similarity).
LIPID 2 2 N-myristoyl glycine (By similarity). |
Keyword | Cell membrane; Cell shape; Complete proteome; Cytoplasm; Cytoskeleton; Erythrocyte maturation; Lipoprotein; Membrane; Myristate; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 691 AA |
Protein Sequence | MGQALSIKSC DFHAAENNEE HYTKAISSQH LTLRRGQSFT ITLNFRAPTH TFLSALKKVA 60
LIAQTGEQPS KINKTQAIFP ISSLGDQKGW SAAVEERDAQ HWTVSVTTPV DAVIGHYSLL 120
LQVSGKKQYP LGQFTLLFNP WNRDDAVFLQ NEAERTEYVL NQNGFIYLGT ADCIQEEPWD 180
FGQFEKDVMD LSLKLLSMDK QVKDWNQPAH VARVVGALLH ALKKKSVLPI SQTQAAQEGA 240
LLYKRRGSVP ILRQWLTGQG RAVYETQAWV SAAVACTVLR CLGIPARVVT TFDSAQGTVG 300
SLLVDEYYNE EGLQNGEGQR GHIWVFQTSV ECWMNRPDLS QGYGGWQILH PRAPNGAGVL 360
GSCSLVPVRA VKEGELQLDP AVPELFAAVN ASCVVWKCCE DGKLELTNSN RKDVGNCIST 420
KVVGSDRCED ITQNYKYPAG SLQEKEVLEK VQKERLKLGK DNGMCPPSCE PWDPLHMFFE 480
ASSSIPLSGD GQLSVTLINP TDEEKKVHLV IGAQALYYNG VLAAGLWSKK QLFMLKPNQV 540
MRLSTNLSFS CFEQTPPENS FLRVTAMARY SHTSLSCFAQ ENMAIGKPDL IIEMPKRAAQ 600
YRPLTVSVRM HNSLEAPMQN CIISIFGRGL IHREKRYGLG SLWPGSSLHT QFQFTPTHLG 660
LQRLTVEVDC DMFQNLTGYR SVLVVAPEVS V 691 |
Gene Ontology | GO:0030863; C:cortical cytoskeleton; IDA:MGI. GO:0016020; C:membrane; IDA:MGI. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro. GO:0000902; P:cell morphogenesis; IMP:MGI. GO:0043249; P:erythrocyte maturation; IEA:UniProtKB-KW. GO:0020027; P:hemoglobin metabolic process; IMP:MGI. GO:0055072; P:iron ion homeostasis; IMP:MGI. GO:0018149; P:peptide cross-linking; IEA:InterPro. GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. GO:0048536; P:spleen development; IMP:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |