UniProt Accession

 RPB11_YEAST; P38902; D6W262 

Genbank Protein ID

 S62624; Z74747; AY557998; BK006948 

Genbank Nucleotide ID

 AAB27135.1; CAA99004.1; AAS56324.1; DAA10778.1 

Protein Name

 DNA-directed RNA polymerase II subunit RPB11 

Protein Synonyms/Alias

 RNA polymerase II subunit B11; B13.6; DNA-directed RNA polymerase II 13.6 kDa polypeptide 

Gene Name

 RPB11 

Gene Synonyms/Alias

 YOL005C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
20	GEGESKLKIDPDTKA	ubiquitination	[1]
84	TTEGYDPKDALKNAC	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft. Seems to be involved transcript termination. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; DNA-directed RNA polymerase; Nucleus; Reference proteome; Transcription. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 120 AA 

Protein Sequence

Gene Ontology

 GO:0005665; C:DNA-directed RNA polymerase II, core complex; IDA:SGD.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
 GO:0006369; P:termination of RNA polymerase II transcription; IMP:SGD. 

Interpro

 IPR009025; DNA-dir_RNA_pol_RBP11-like.
 IPR008193; RNA_pol_Rpb11_13-16kDa_CS. 

Pfam

  

SMART

  

PROSITE

 PS01154; RNA_POL_L_13KD 

PRINTS