CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032935
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Connector enhancer of kinase suppressor of ras 3 
Protein Synonyms/Alias
  
Gene Name
 CNKSR3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
225NFTPAPLKNLRWKPPubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MKNLVLKLRA SSHNLQNYIS SRRKSPAYDG NTSRKAPNEF LTSVVELIGA AKALLAWLDR 60
APFTGITDFS VTKNKIIQLC LDLTTTVQKD CFVAEMEDKV LTVVKVLNGI CDKTIRSTTD 120
PVMSQCACLE EVHLPNIKPG EGLGMYIKST YDGLHVITGT TENSPADRSQ KIHAGDEVIQ 180
VNQQTVVGWQ LKNLVKKLRE NPTGVVLLLK KRPTGSFNFT PAPLKNLRWK PPLVQTSPPP 240
ATTQSPESTM DTSLKKEKSA ILDLYIPPPP AVPYSPRDEN GSFVYGGSSK CKQPLPGPKG 300
SESPNSFLDQ ESRRRRFTIA DSDQLPGYSV ETNILPTKMR EKTPSYGKPR PLSMPADGNW 360
MGIVDPFARP RGHGRKGEDA LCRYFSNERI PPIIEESSSP PYRFSRPTTE RHLVRGADYI 420
RGSRCYINSD LHSSATIPFQ EEGTKKKSGS SATKSSSTEP SLLVSWFTRL KLLTH 475 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0009966; P:regulation of signal transduction; IEA:InterPro. 
Interpro
 IPR010599; CNKSR2.
 IPR017874; CRIC_domain.
 IPR019555; CRIC_domain_Chordata.
 IPR001478; PDZ. 
Pfam
 PF10534; CRIC_ras_sig
 PF06663; DUF1170
 PF00595; PDZ 
SMART
 SM00228; PDZ 
PROSITE
 PS51290; CRIC
 PS50106; PDZ 
PRINTS