CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021709
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Translin-associated protein X 
Protein Synonyms/Alias
 Translin-associated factor X 
Gene Name
 Tsnax 
Gene Synonyms/Alias
 Trax 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
4****MNGKEGPGGFRacetylation[1]
27HNQRREGKDASSSSPacetylation[1]
68RDITVESKRTIFLLHacetylation[1]
161FTTDDSGKESKAPPAacetylation[1]
241TGPYEVSKKLYTLKQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (By similarity). 
Sequence Annotation
 REGION 73 208 Interaction with C1D (By similarity).
 METAL 129 129 Magnesium (By similarity).
 METAL 197 197 Magnesium (By similarity).
 MOD_RES 237 237 Phosphotyrosine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Developmental protein; Differentiation; DNA-binding; Golgi apparatus; Magnesium; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Spermatogenesis; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 290 AA 
Protein Sequence
MNGKEGPGGF RKRKHDNFPH NQRREGKDAS SSSPVMLAFK SFQQELDTRH DKYERLVKLS 60
RDITVESKRT IFLLHRITSA PDMEEILTES ESKLDGVRQK MLQVAQELSG EDMHQFHRAV 120
TTGLQEYVEA VSFQHFIRTR SLISMEEINR QLTFTTDDSG KESKAPPADG QDKQLVTWRL 180
KITPVDYLLG VADLTGELMR MCINSVGNGD IDTPFEVSQF LRQVYDGFSF IGNTGPYEVS 240
KKLYTLKQSL SKVENACYAL KVRGSEIPKH MLADVFSVKT EMIDQEESIS 290 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0032403; F:protein complex binding; IDA:RGD.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. 
Interpro
 IPR002848; Translin.
 IPR016069; Translin_C.
 IPR016068; Translin_N. 
Pfam
 PF01997; Translin 
SMART
  
PROSITE
  
PRINTS