CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038356
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Kank1 
Protein Synonyms/Alias
  
Gene Name
 Kank1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
941EAETAEGKHSRGHEQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1360 AA 
Protein Sequence
MAYTTKVNGC AAEKADGVLN GDHNKEKKDP YFVETPYGFQ LDLDFVKYVD DIQKGNTIKK 60
LNIQKRRKPS VPCPEVRAIP GHQGVWTSTE SLSSSNSDDS KQCPSFLLAR SHVTSTPIPR 120
PPAPLETSPT FAVSENRQLL PPPSPQLPRH NLHVTKTLME TRRRLEQERV TMQMAPGDFR 180
RPRLASFGGM GSTSSLPSFV GSANHSSAIH QLQNGYQGNG DYNSYVPAAP TTSSMGSSVR 240
HSPLSSGIST PVTNVSPMHL QHIREQMAIA LKRLKELEEQ VRTIPVLQVK ISVLQEEKRQ 300
LASQLKSQRA SSQNEACGVR KRSYSAGNAS QLELLARARR GGGELYIDYE EEEMESVEQS 360
TQRIQEFRQL TADMQALERK IQDSSCEVAS ELRENGQCPS RECKSVAVGS DENMNDVVVY 420
HRDLRPCKDT AVGTVTETRN VGISVTEAML GVITEADKEI ELQQQTIEAL KEKIYRLEVQ 480
LKETTHDREM TKLKQELQAA GSRKKVDKAT MAQPLVFSKL VEALVPTRDQ MVGSHVDTRE 540
SCVGTSVQTS SVGTSCHPDC KNQVVGSELP MNWWVVKERV AMHDQCVGRS VETCDRSVGV 600
EVSVCETGSN TEASGSDLTL LKTNLNLKDV RSIGCGDCSV DVIVCFPKEC TSRSMNTEAV 660
GQEEAAVMAV PHTTDQHTST NLERVDQCTN TEAATLVESC TNTLLSTMDK QTSTQTVEMR 720
TVAIGEGRVR DINPSTKTRS VGVGTVLSGN SEFDRPCAVK TKESGVGQIN IQDNYLVGLK 780
MRTIACGPPQ LTVGLMGSRR SVGVGNEPVG ELPEESPQPR VASGMVTGLD HYIERVQRLL 840
AEQQTLLAEN YSELAEAFGE PHSQIGSLNS QLISTLSSIN SVMKSASTEE LRNSDFQKAS 900
LGKTTGNHLE YTCKCGGLRS GGLLNVQPSQ PEVEAETAEG KHSRGHEQFP MQGSTLPPVN 960
LTDDQIATGL YVCPNNENTL KSIMKKSDGN KDSNGAKKNL QFIGINGGYE TTSSDESSSD 1020
GSSSSESDDE CDTIGYPPEE EEEEEEKDHD TRGMAEGHHA VNIEGFKSAR VEDEVQVPEC 1080
EPEKEEIRER YELSEKMLSA CNLLKYNIKD PKALASKDMR ICLNTLQHDW FRVSSQKSAV 1140
PAMVGDYIAA FEAVSPDVLR YIINMADGNG NTALHYSVSH SNFQIVKLLL DADVCNVDHQ 1200
NKAGYTPIML AALAAVEAEK DMQVVEELFS CGDVNAKASQ AGQTALMLAV SHGRIDMVKG 1260
LLACGADVNI QDDEGSTALM CASEHGHVEI VKLLLAQPGC NGHLEDNDGS TALSIALEAG 1320
HKDIAVLLYA HLNFSKAQSP STPRLGRKTS PGPTHRGSFD 1360 
Gene Ontology
 GO:0032587; C:ruffle membrane; IEA:Compara.
 GO:0030837; P:negative regulation of actin filament polymerization; ISO:MGI.
 GO:0030336; P:negative regulation of cell migration; IEA:Compara.
 GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Compara.
 GO:2000393; P:negative regulation of lamellipodium morphogenesis; IEA:Compara.
 GO:0010977; P:negative regulation of neuron projection development; IEA:Compara.
 GO:0035024; P:negative regulation of Rho protein signal transduction; IEA:Compara.
 GO:1900028; P:negative regulation of ruffle assembly; IEA:Compara.
 GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; IEA:Compara.
 GO:0035413; P:positive regulation of catenin import into nucleus; IEA:Compara.
 GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IEA:Compara.
 GO:0090303; P:positive regulation of wound healing; IEA:Compara.
 GO:2000114; P:regulation of establishment of cell polarity; IEA:Compara. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR021939; KN_motif. 
Pfam
 PF12796; Ank_2
 PF12075; KN_motif 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS