CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017789
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Abhydrolase domain-containing protein 8 
Protein Synonyms/Alias
  
Gene Name
 Abhd8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
318AKEKQLLKEGNAFNVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 ACT_SITE 244 244 Charge relay system (By similarity).
 ACT_SITE 362 362 Charge relay system (By similarity).
 ACT_SITE 390 390 Charge relay system (By similarity).  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 439 AA 
Protein Sequence
MTSEHTMLTG VTDGFFCCLL GTPPNAVRPL ESVESSDGYT FVEVKPGRVL RVKHAGPAPI 60
PTPPPPPPED DPGVKTGLVR CQRRITVYRN GRLVVENLGR APRADLQGRS GSGDPPAALE 120
VELAEPAGGD TRANPGSGRR RRPRRPKRTI HIDCEQRITS CKGAQADVVL FFIHGVGGSL 180
AIWKEQLDFF VRLGYEVVAP DLAGHGASSA PQVAAAYTFY ALAEDMRAIF TRYAKKRNVL 240
IGHSYGVSFC TFLAHEYPDL VHKVIMINGG GPTALEPSLC SIFNMPTCVL HCLSPCLAWS 300
FLKAGFARQG AKEKQLLKEG NAFNVSSFVL RAMMSGQYWP EGDEVYHAEL TVPVLLVHGM 360
HDKFVPVEED QRMAEILLLA FLKLIEEGSH MVMLECPETV NTLLHEFLLW EPEPEAEPKL 420
EPKPKPQLLQ PEPAPGEEK 439 
Gene Ontology
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR000073; AB_hydrolase_1.
 IPR000639; Epox_hydrolase-like. 
Pfam
  
SMART
  
PROSITE
  
PRINTS
 PR00111; ABHYDROLASE.
 PR00412; EPOXHYDRLASE.