UniProt Accession

 B4E0G4_HUMAN; B4E0G4 

Genbank Protein ID

 AC004383; AL591668; AK303369 

Genbank Nucleotide ID

 BAG64426.1 

Protein Name

 PHD finger protein 6 

Protein Synonyms/Alias

 cDNA FLJ60207, highly similar to PHD finger protein 6 

Gene Name

 PHF6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
8	MSSSVEQKKGPTRQR	ubiquitination	[1]
38	LLISENQKVAAHHKC	ubiquitination	[1]
78	YHCALHDKAQIREKP	ubiquitination	[1]
84	DKAQIREKPSQGIYM	ubiquitination	[1]
139	RPRKTNFKGLSEDTR	ubiquitination	[1]
193	EENEARGKLHIFNAK	ubiquitination	[1]
232	EFGDFDIKTVLQEIK	ubiquitination	[1]
239	KTVLQEIKRGKRMKC	ubiquitination	[1, 2]
245	IKRGKRMKCTLCSQP	ubiquitination	[1, 3]
276	YHCGVQDKAKYIENM	ubiquitination	[1]
278	CGVQDKAKYIENMSR	ubiquitination	[1]
315	RESKSRGKVEIDQQQ	ubiquitination	[3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 331 AA 

Protein Sequence

Gene Ontology

 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR001965; Znf_PHD. 

Pfam

  

SMART

 SM00249; PHD 

PROSITE

  

PRINTS