UniProt Accession

 MMGT1_HUMAN; Q8N4V1; B2R625; B4DIY3; D3DWG7; Q5JPP7 

Genbank Protein ID

 AK295829; AK312409; AL732579; AL953870; CH471150; CH471150; BC033588 

Genbank Nucleotide ID

 BAG58645.1; BAG35322.1; CAI39920.2; CAI39920.2; EAW88483.1; EAW88485.1; AAH33588.1 

Protein Name

 Membrane magnesium transporter 1 

Protein Synonyms/Alias

 ER membrane protein complex subunit 5; Transmembrane protein 32 

Gene Name

 MMGT1 

Gene Synonyms/Alias

 EMC5; TMEM32 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
77	MDATSELKNKTFDTL	ubiquitination	[1]
122	LSSNTSLKLRKLESL	ubiquitination	[1, 2, 3, 4]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Mediates Mg(2+) transport (By similarity). 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Endoplasmic reticulum; Endosome; Golgi apparatus; Magnesium; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 131 AA 

Protein Sequence

Gene Ontology

 GO:0005769; C:early endosome; ISS:UniProtKB.
 GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
 GO:0072546; C:ER membrane protein complex; IDA:UniProtKB.
 GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0015095; F:magnesium ion transmembrane transporter activity; ISS:UniProtKB. 

Interpro

 IPR018937; Magnesium_transport. 

Pfam

 PF10270; MMgT 

SMART

  

PROSITE

  

PRINTS