UniProt Accession

 T2AG_MOUSE; Q80ZM7 

Genbank Protein ID

 BC048705 

Genbank Nucleotide ID

 AAH48705.1 

Protein Name

 Transcription initiation factor IIA subunit 2 

Protein Synonyms/Alias

 General transcription factor IIA subunit 2; Transcription initiation factor IIA gamma chain; TFIIA-gamma 

Gene Name

 Gtf2a2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
89	REVTELIKVDKVKIV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 109 AA 

Protein Sequence

Gene Ontology

 GO:0005672; C:transcription factor TFIIA complex; IEA:Compara.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IEA:Compara. 

Interpro

 IPR009083; TFIIA_a-hlx.
 IPR009088; TFIIA_b-brl.
 IPR003194; TFIIA_gsu.
 IPR015871; TFIIA_gsu_C.
 IPR015872; TFIIA_gsu_N. 

Pfam

 PF02751; TFIIA_gamma_C
 PF02268; TFIIA_gamma_N 

SMART

  

PROSITE

  

PRINTS