UniProt Accession

 PIGP_HUMAN; P57054; B2RB18; B2RE99; B5BU92; D3DSG7; J3KR75; Q53Y28; Q96KI1; Q9NZA6 

Genbank Protein ID

 AB037162; AB037163; AB037164; AB035742; AB035743; AB035744; AB035745; AF216305; AB039659; AF237812; BT007053; AK314457; AK316609; AB451328; AB451472; AP000704; AP001429; AP001431; AP001727; CH471079; CH471079; CH471079; CH471079; CH471079; BC005180; BC011007 

Genbank Nucleotide ID

 BAA96871.1; BAA96872.1; BAA96873.1; BAA95633.1; BAA95634.1; BAA95635.1; BAA95636.1; AAF32289.1; BAB12395.1; AAG09757.1; AAP35702.1; BAG37065.1; BAG38196.1; BAG70142.1; BAG70286.1; BAA95512.1; EAX09724.1; EAX09725.1; EAX09727.1; EAX09726.1; EAX09728.1; AAH05180.1; AAH11007.1 

Protein Name

 Phosphatidylinositol N-acetylglucosaminyltransferase subunit P 

Protein Synonyms/Alias

 Down syndrome critical region protein 5; Down syndrome critical region protein C; Phosphatidylinositol-glycan biosynthesis class P protein; PIG-P 

Gene Name

 PIGP 

Gene Synonyms/Alias

 DCRC; DSCR5; DSCRC; NPD010 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
126	AKNQQQKKYQEEAIP	ubiquitination	[1]
157	AAKELYTKN******	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Direct protein sequencing; Glycosyltransferase; GPI-anchor biosynthesis; Membrane; Polymorphism; Reference proteome; Transferase; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 158 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
 GO:0000506; C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; IDA:MGI.
 GO:0016021; C:integral to membrane; NAS:UniProtKB.
 GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:EC.
 GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
 GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome. 

Interpro

 IPR013717; PIG-P.
 IPR016542; PIG-P_GPI19. 

Pfam

 PF08510; PIG-P 

SMART

  

PROSITE

  

PRINTS