CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032677
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CDK1, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_002610 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
1303GAQSLSGKDGGKEKQacetylation[1]
1307LSGKDGGKEKQGAVGacetylation[1, 2]
1309GKDGGKEKQGAVGREacetylation[2]
1726RTWYPGEKEPRGCERacetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1833 AA 
Protein Sequence
MDASASPDTP STASSLLSSV LRRLLHPLFS SCAPNSPFSP QSPVPGPLDS HSSSSDALRP 60
RSSSACIPDS GRQLASSLPS PSSSSAVSPA TALPTSSLSV PFLTEERRRR ILEELQRRCE 120
QPPVLIVPAS GSEEACGVRF LQPFFLAAKG EDSEETEEET SSSLSHRGIP PSVQILLSVF 180
DSQLREIQTT LAQSERTAEG KEAAHERGAS AEGVSVSAGP FSDSEEELLR DEASLLLLRR 240
RCLQWVGLWR VATHAFSPSD RKRLRRFVDR EKRKWEQTEN TASHLSTSQD HVSAPSCPSS 300
SSPSSSSSSS SAVCVRSKGE AERGDARGDW EWGGGSQSPE ESNKKRERVS SESRGAGEEN 360
RKETRRSKKA RTFYVMPMSD AGSYPSSSLT LNNFVKVQQV GQGAYGDVWL AEDVKNRRWV 420
AMKKMKIMAP PPGALPANNP PHALAPRQEE HAKSRKVERE EKTREEKPTE KGGAAAVAAA 480
CQQMNNAGEE REGFPRTAIR EICLLNELSK CKHTVELLAV VHSKPRLKDR HHRGAVWMVF 540
EYLPFDLLGF LDAIRDSKEK REKYTRPQTW LSIGEIKGIL LQLFTALHHC HRKNVVHRDL 600
KSANLLMDTD GTVKLADFGL ARKFTNEKPA LTNRVITLWY RPPELLLGSE AYDGSVDMWS 660
AGCIMAELVC GMPLFAADKE AALLRQIVEK IGPPSESDLA SLRALCPQHF RNLSGRGDGF 720
ARDPVFDGSG VDRSLEIQRL FKYRNQIGDE GWDLLRQLLA WNPATRITAR AALQHRWFST 780
HPLPKRVEKR ANLHAAHSYV SKHAQRRGGR DQRQMGGTSH ARKGPGREGS ADETRSERVS 840
VGEVRLAAWA RSVERKAARL EALRQLYSER QKQDESSRRS LPHSLPASTV SGVSTHERES 900
SESILPSLSS SLVHPIPGRP SLSQVSGGGS QASFVSADLF PRKKREAFVQ LPRESGSDLK 960
DLPWQTADDR GEEREKGEVR REEEKHDSLP ASLVSPPPVS THFSPGSWND HAEQTDGRSD 1020
RRHYGREDRE GRRGREGAFD SLHATKEGVY GRCLREEEKR REQLRGSSGR RRSLDSEERE 1080
SHPASRSGDK KRGRETERSN RGRREEGRRG ENRPAFSPER PAFDESRRRG RERLSLHSAF 1140
ASGGALKEDG RASLEASPVH ASPGGSVSDM TNSSDEETKR RRGPDSARAG AESYQAIHGG 1200
EKSEGDSGKW RHARWPEWDK KAKIRDRAAE RDYARCQGES VHAERHWAEE KSQSPSFSVS 1260
PDPPGSCGDY RRGEDAGVGD SRRMRKRASE ETERCGAQSL SGKDGGKEKQ GAVGREACEF 1320
GVEALSPVSL ALFFPTHAEG CEDKKRSEKT GEAEANSSAV AKKQEERRRK AFDLFKRAAE 1380
SKSGAASRGE STHAGSAEKE KLAKGRNHDD AGEVLGGSDD GRVRGEKRSS SLKGTREETR 1440
DARDRETEET PPGEEMESQV GYRHGRRRAG WRDAEELDRE RMEERDVEEE KPFSCLLRDP 1500
CVEHRSPVNQ EDPKRLSLPS VDSQLSSPDG GTPGVGRREE EARRHRGCDT VEEGERGMLG 1560
SNAYRRRDRG SGLYTRERDA ESGERRRRRP QEASLSSRHE RERKEEPLFL NRSSAHSSHS 1620
VSPFSPRHDD DIRGRDRKRR YPSLGAPCLS KEGRSLLFGV SLGSPVLGES RAMSSPSPVF 1680
SRSEPQSRLA LQDEAERRRR GDRGETTSAV ESRGNGKART WYPGEKEPRG CERASDLCRS 1740
ERASLGREDR AAHRPKDRRR DGEGQRRRHE EGGEGRESCD QFRERTSVRS TYNVDTHRRR 1800
GDDEKGRRKA RDGKRRRVSD DKGGDSRPVS RRS 1833 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS