CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011179
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase III subunit RPC10 
Protein Synonyms/Alias
 RNA polymerase III subunit C10; DNA-directed RNA polymerases III 12.5 kDa polypeptide; RNA polymerase III subunit C11 
Gene Name
 RPC11 
Gene Synonyms/Alias
 YDR045C; YD9609.01C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
49DRKKLPRKEVDDVLGubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Involved in Pol III transcription reinitiation and RNA cleavage during transcription termination. 
Sequence Annotation
 ZN_FING 5 29 C4-type (Potential).
 ZN_FING 65 108 TFIIS-type.  
Keyword
 3D-structure; Complete proteome; DNA-directed RNA polymerase; Metal-binding; Nucleus; Reference proteome; Transcription; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 110 AA 
Protein Sequence
MLSFCPSCNN MLLITSGDSG VYTLACRSCP YEFPIEGIEI YDRKKLPRKE VDDVLGGGWD 60
NVDQTKTQCP NYDTCGGESA YFFQLQIRSA DEPMTTFYKC VNCGHRWKEN 110 
Gene Ontology
 GO:0005666; C:DNA-directed RNA polymerase III complex; IDA:SGD.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006386; P:termination of RNA polymerase III transcription; IMP:SGD.
 GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IDA:SGD. 
Interpro
 IPR019761; DNA-dir_RNA_pol-M_15_CS.
 IPR001529; DNA-dir_RNA_pol_M/15kDasu.
 IPR012164; DNA-dir_RNApol_C11.
 IPR001222; Znf_TFIIS. 
Pfam
 PF02150; RNA_POL_M_15KD
 PF01096; TFIIS_C 
SMART
 SM00661; RPOL9
 SM00440; ZnF_C2C2 
PROSITE
 PS01030; RNA_POL_M_15KD
 PS00466; ZF_TFIIS_1
 PS51133; ZF_TFIIS_2 
PRINTS