CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044327
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Echinoderm microtubule-associated protein-like 5 
Protein Synonyms/Alias
  
Gene Name
 EML5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
913AALAPGSKGLLLEDNubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1931 AA 
Protein Sequence
MAARSAPSCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICIW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR 120
LVSVGLDSKN AVCVWDWKRG KMLSMAPGHT DRIFDISWDL YQPNKLVSCG VKHIKFWSLC 180
GNALTPKRGV FGKTGDLQTI LCLACARDEL TYSGALNGDI YVWKGINLIR TIQGAHAAGI 240
FSMNACEEGF ATGGRDGCIR LWDLTFKPIT VIDLRETDQG YKGLSVRSVC WRGDHILVGT 300
QDSEIFEIVV QERNKPFLIM QGHCEGELWA LAVHPTKPLA VTGSDDRSVR IWSLVDHALI 360
ARCNMEEPIR CAAVNADGIH LALGMKDGSF TVLRVRDMTE VVHIKDRKEA IHELKYSPDG 420
TYLAVGCNDS SVDIYGVAQR YKKVGECLGS LSFITHLDWS SDSRYLQTND GNGKRLFYRM 480
PGGKEVTSTE EIKGVHWASW TCVSGLEVNG IWPKYSDIND INSVDGNYIG QVLVTADDYG 540
IIKLFRYPCL RKGAKFRKYI GHSAHVTNVR WSHDYQWVIS IGGADHSVFQ WKFIPERKLK 600
DAVHIAPQES LADSHSDESD SDLSDVPELD SEIEQETQLT YRRQVYKEDL PQLKEQCKEK 660
QKSATSKRRE RAPGNSIRLH FVHGYRGYDC RSNLFYTQIG EIVYHVAAVG VIYNRQQNTQ 720
RFYLGHDDDI LCLTIHPLKD YVATGQVGRD PSIHIWDTET IKPLSILKGH HQYGVSAVDF 780
SADGKRLASV GIDDSHTVVL WDWKKGEKLS IARGSKDKIF VVKMNPYVPD KLITAGIKHM 840
KFWRKAGDVC IWRDIFLVKT VKAHDGPVFS MHALEKGFVT GGKDGIVALW DDSFERCLKT 900
YAIKRAALAP GSKGLLLEDN PSIRAISLGH GHILVGTKNG EILEVDKSGP ITLLVQGHME 960
GEVWGLATHP YLPICATVSD DKTLRIWDLS PSHCMLAVRK LKKGGRCCCF SPDGKALAVG 1020
LNDGSFLMAN ADTLEDLVSF HHRKDMISDI RFSPGSGKYL AVASHDSFID IYNVMSSKRV 1080
GICKGATSYI THIDWDIRGK LLQVNTGAKE QLFFEAPRGK KQTIPSVEVE KIAWASWTSV 1140
LGLCCEGIWP VIGEVTDVTA SCLTSDKMVL ATGDDLGFVK LFRYPTKGKF GKFKRYVAHS 1200
THVTNVRWTY DDSMLVTLGG TDMSLMVWTN EMEGYREKRP CDSEESDIDS EEDGGYDSDV 1260
TRENEISYTI RALSTNIRPM LGIKPHLQQK EPSIDERPPV SRAPPQPEKL QTNNVGKKKR 1320
PIEDLVLELI FGYRGRDCRN NVHYLNDGDD IIYHTASVGI LHNVATGSQS FYQEHNDDIL 1380
CLTVNQHPKF INIVATGQVV LSCSLLTTAP SIHIWDAMNK QTLSILRCYH SKGVCSVSFS 1440
ATGKLLLSVG LDPEHTITIW RWQEGAKIAS RAGHNQRIFV AEFRPDSDTQ FVSVGVKHVK 1500
FWTLAGRALL SKKGLLSTLE DARMQTMLAI AFGANNLTFT GTISGDVCVW KDHILCRIVA 1560
RAHNGPVFAM YTTLRDGLIV TGGKERPSKE GGAVKLWDQE LRRCRAFRLE TGQATDCVRS 1620
VCRGKGKILV GTRNAEIIEV GEKNAACNIL VNGHVDGPIW GLATHPSRDF FLSAAEDGTV 1680
RLWDIADKKM LNKVNLGHAA RTVCYSPEGD MVAIGMKNGE FIILLVSSLK IWGKKRDRRC 1740
AIHDIRFSPD SRYLAVGSSE NSVDFYDLTL GPTLNRISYC KDIPSFVIQM DFSADSSYLQ 1800
VSSGCYKRHV YEVPSGKHLM DHAAIDRITW ATWTSILGDE VLGIWSRHAE KADVNCACVS 1860
HSGISLVTGD DFGMVKLFDF PCPEKFAKHK RFLGHSPHVT NIRFTSGDRH VVSAGGDDCS 1920
LFVWKCVHTP H 1931 
Gene Ontology
  
Interpro
 IPR005108; HELP.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF03451; HELP
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS