| Tag | Content |
|---|
| CPLM ID | CPLM-018545 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | E3 ubiquitin-protein ligase RNF167 |
Protein Synonyms/Alias | RING finger protein 167 |
Gene Name | Rnf167 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 223 | IPTHDYQKGDEYDVC | ubiquitination | [1] | | 272 | RKTCPICKQPVHRGP | ubiquitination | [1] |
|
Reference | [1] BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Mathew R, Seiler MP, Scanlon ST, Mao AP, Constantinides MG, Bertozzi-Villa C, Singer JD, Bendelac A. Nature. 2012 Nov 22;491(7425):618-21. [ PMID: 23086144] |
Functional Description | May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition (By similarity). |
Sequence Annotation | DOMAIN 48 152 PA.
ZN_FING 230 272 RING-type; atypical.
CARBOHYD 79 79 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Ligase; Membrane; Metal-binding; Reference proteome; Signal; Transmembrane; Transmembrane helix; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 347 AA |
Protein Sequence | MHPAAFPLPV VVATVLWGAA PVRGLIRATS EHNASMDFAD LPALFGATLS DEGLQGFLVE 60
AHPENACGPI APPPSAPVNG SVFIALLRRF DCNFDLKVLN AQKAGYGAAV VHNVNSNELL 120
NMVWNSEEIQ QQIWIPSVFI GERSAEYLRA LFVYEKGARV LLVPDNSFPL GYYLIPFTGI 180
VGLLVLAMGT VLIVRCIQHR KRLQRNRLTK EQLKQIPTHD YQKGDEYDVC AICLDEYEDG 240
DKLRVLPCAH AYHSRCVDPW LTQTRKTCPI CKQPVHRGPG DEEQEEETQE QEEGDEGEPR 300
DQPASEWTPL LGSSPTLPTS FGSLAPAPLV FPGPSTDPSP PSSAALA 347 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:Compara. GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0045786; P:negative regulation of cell cycle; IEA:Compara. GO:0000209; P:protein polyubiquitination; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |