UniProt Accession

 G3UWL2_MOUSE; G3UWL2 

Genbank Protein ID

 AC109204 

Genbank Nucleotide ID

  

Protein Name

 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 

Protein Synonyms/Alias

  

Gene Name

 Ppp2r1a 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
79	ADKFTEVKEFCENLS	acetylation	[1]
79	ADKFTEVKEFCENLS	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 143 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:MGI.
 GO:0000159; C:protein phosphatase type 2A complex; IDA:MGI.
 GO:0004722; F:protein serine/threonine phosphatase activity; IDA:MGI.
 GO:0070262; P:peptidyl-serine dephosphorylation; IDA:MGI.
 GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:MGI. 

Interpro

 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000357; HEAT.
 IPR021133; HEAT_type_2. 

Pfam

 PF02985; HEAT 

SMART

  

PROSITE

 PS50077; HEAT_REPEAT 

PRINTS