UniProt Accession

 EF1B_MOUSE; O70251; Q3THP5; Q5SUH1; Q8CHS1; Q99L22; Q9CZD4 

Genbank Protein ID

 AF029844; AK012756; AK027911; AK168191; AL645950; BC003899; BC023139; BC039635 

Genbank Nucleotide ID

 AAC13264.2; BAB28447.1; BAC25661.1; BAE40151.1; CAI24121.1; AAH03899.1; AAH23139.1; AAH39635.1 

Protein Name

 Elongation factor 1-beta 

Protein Synonyms/Alias

 EF-1-beta 

Gene Name

 Eef1b 

Gene Synonyms/Alias

 Eef1b2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
7	*MGFGDLKTPAGLQV	ubiquitination	[1]
60	LRWYNHIKSYEKEKA	ubiquitination	[1]
78	GVKKSLGKYGPSSVE	acetylation	[2]
78	GVKKSLGKYGPSSVE	ubiquitination	[1]
147	SSILLDVKPWDDETD	ubiquitination	[1]
176	GLVWGSSKLVPVGYG	acetylation	[2, 3]
176	GLVWGSSKLVPVGYG	ubiquitination	[1]
185	VPVGYGIKKLQIQCV	acetylation	[2]
185	VPVGYGIKKLQIQCV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

 EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP (By similarity). 

Sequence Annotation

 DOMAIN 2 90 GST C-terminal.
 MOD_RES 7 7 N6-acetyllysine (By similarity).
 MOD_RES 83 83 Phosphoserine.
 MOD_RES 106 106 Phosphoserine.  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Elongation factor; Phosphoprotein; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 225 AA 

Protein Sequence

Gene Ontology

 GO:0005853; C:eukaryotic translation elongation factor 1 complex; ISS:MGI.
 GO:0003746; F:translation elongation factor activity; ISS:MGI. 

Interpro

 IPR018940; EF-1_beta_acid_region_euk.
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR014717; Transl_elong_EF1B/ribosomal_S6.
 IPR001326; Transl_elong_EF1B_B/D_CS.
 IPR014038; Transl_elong_fac_EF1B_bsu/dsu. 

Pfam

 PF10587; EF-1_beta_acid
 PF00736; EF1_GNE 

SMART

 SM00888; EF1_GNE 

PROSITE

 PS00824; EF1BD_1
 PS00825; EF1BD_2
 PS50405; GST_CTER 

PRINTS