CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042028
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Inactive ubiquitin carboxyl-terminal hydrolase 54 
Protein Synonyms/Alias
  
Gene Name
 USP54 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
92QFQCSSEKVLPSDTLubiquitination[1]
105TLRSALAKTFQDEQRubiquitination[1, 2]
203CMLERREKPSPSMFGubiquitination[1]
331KEIGPKWKDVVTKCIubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 744 AA 
Protein Sequence
MSWKRNYFSG GRGSVQGMFA PRSSTSIAPS KGLSNEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTTHKCM GDSCIFCALK GIFNQFQCSS EKVLPSDTLR SALAKTFQDE QRFQLGIMDD 120
AAECFENLLM RIHFHIADET KEDICTAQHC ISHQKFAMTL FEQCVCTSCG ATSDPLPFIQ 180
MVHYISTTSL CNQAICMLER REKPSPSMFG ELLQNASTMG DLRNCPSNCG ERIRIRRVLM 240
NAPQIITIGL VWDSDHSDLA EDVIHSLGTC LKLGDLFFRV TDDRAKQSEL YLVGMICYYG 300
KHYSTFFFQT KIRKWMYFDD AHVKEIGPKW KDVVTKCIKG HYQPLLLLYA DPQGTPVSTQ 360
DLPPQAEFQS YSRTCYDSED SGREPSISSD TRTDSSTESY PYKHSHHESV VSHFSSDSQG 420
TVIYNVENDS MSQSSRDTGH LTDSECNQKH TSKKGSLIER KRSSGRVRRK GDEPQASGYH 480
SEGETLKEKQ APRNASKPSS STNRLRDFKE TVSNMIHNRP SLASQTNVGS HCRGRGGDQP 540
DKKPPRTLPL HSRDWEIEST SSESKSSSSS KYRPTWRPKR ESLNIDSIFS KDKRKHCGYT 600
QLSPFSEDSA KEFIPDEPSK PPSYDIKFGG PSPQYKRWGP ARPGSHLLEQ HPRLIQRMES 660
GYESSERNSS SPVSLDAALP ESSNVYRYCL AFEQQHCLLQ QCEPPTWGFQ AWLRQVEGWP 720
LLLSLCALST SYNNSTLCWK NRGT 744 
Gene Ontology
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR001394; Peptidase_C19. 
Pfam
 PF00443; UCH 
SMART
  
PROSITE
 PS50235; UCH_2_3 
PRINTS