CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008271
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 High-affinity methionine permease 
Protein Synonyms/Alias
  
Gene Name
 MUP1 
Gene Synonyms/Alias
 YGR055W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
16SQLNVFNKENYQFSSubiquitination[1]
27QFSSSTTKKEVSNSTubiquitination[1]
28FSSSTTKKEVSNSTVubiquitination[1, 2]
526GHYKLVSKDVLGEDGubiquitination[1]
567TNIIEHYKSEQEKSLubiquitination[1]
572HYKSEQEKSL*****ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 High affinity permease for methionine. 
Sequence Annotation
 MOD_RES 552 552 Phosphothreonine.
 MOD_RES 573 573 Phosphoserine.  
Keyword
 Amino-acid transport; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 574 AA 
Protein Sequence
MSEGRTFLSQ LNVFNKENYQ FSSSTTKKEV SNSTVDADNG ASDFEAGQQF ATELDQGEKQ 60
LGILSCIGLI CNRMLGTGVF AVSSTIYTLC GSVGLALIMW AVGAIIAISG LYVYMEFGTA 120
IPKNGGEKNY LEAIFRKPKF FITCMYAAYI FFLGWAAGNS INTAIMFLTA ADTEVTKWNQ 180
RGIGVAVVFF AFLINSLNVK IGLYLQNILG IFKIGIVLFI SITGWVALGG GLKDGYQSHN 240
FRNAFEGTET ATAYGIVNAL YSVIWSFVGY SNVNYALGEV KNPVRTLKIA GPTSMVFLAI 300
IYIFVNIAYF AVVPKDKLIS SKLILAADFF DIVFGGQAKR AAAALVGLSA LGNVLSVIFS 360
QGRIIQQLGR EGVLPFSNFF ASSKPFNSPM VGLFQHFIVC TVTILAPPPG DAYLLVQNLI 420
SYPMNIINFA ISAGLLWIYW QRRQGKIEWN PPIKAGVFVT GFFTLSNLYL IIAPYVPPSN 480
GESVYSSMPY WIHCVIAWGI FFFGGVYYVV WAQLLPRWGH YKLVSKDVLG EDGFWRVKIA 540
KVYDDTIGDV DTQEDGVIET NIIEHYKSEQ EKSL 574 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; ISS:SGD.
 GO:0000102; F:L-methionine secondary active transmembrane transporter activity; IDA:SGD.
 GO:0042883; P:cysteine transport; IDA:UniProtKB. 
Interpro
 IPR002293; AA/rel_permease1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS