UniProt Accession

 Q3UCS1_MOUSE; Q3UCS1 

Genbank Protein ID

 AK133723; AK150417; AK153327; AK160527; AK160538; AK164074; CH466645 

Genbank Nucleotide ID

 BAE21800.1; BAE29541.1; BAE31906.1; BAE35845.1; BAE35855.1; BAE37614.1; EDL28982.1 

Protein Name

 Ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae), isoform CRA_c 

Protein Synonyms/Alias

  

Gene Name

 Ube2a 

Gene Synonyms/Alias

 mCG_11559 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
66	FTEEYPNKPPTVRFV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Ligase; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 152 AA 

Protein Sequence

Gene Ontology

 GO:0033503; C:HULC complex; IEA:Compara.
 GO:0000790; C:nuclear chromatin; IDA:MGI.
 GO:0001741; C:XY body; IDA:MGI.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0006281; P:DNA repair; IEA:Compara.
 GO:0033522; P:histone H2A ubiquitination; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IGI:MGI.
 GO:0060135; P:maternal process involved in female pregnancy; IMP:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0051865; P:protein autoubiquitination; IEA:Compara.
 GO:0070979; P:protein K11-linked ubiquitination; IEA:Compara.
 GO:0070936; P:protein K48-linked ubiquitination; IEA:Compara.
 GO:0009411; P:response to UV; IEA:Compara. 

Interpro

 IPR000608; UBQ-conjugat_E2.
 IPR023313; UBQ-conjugating_AS.
 IPR016135; UBQ-conjugating_enzyme/RWD. 

Pfam

 PF00179; UQ_con 

SMART

  

PROSITE

 PS00183; UBIQUITIN_CONJUGAT_1
 PS50127; UBIQUITIN_CONJUGAT_2 

PRINTS