CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043629
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dynamin-like 120 kDa protein, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Opa1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
941DFAEDGEKKVKLLTGacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 978 AA 
Protein Sequence
MWRAGRAAVA CEVCQSLVKH SSGIQRNVPL QKLHLVSRSI YRSHHPALKL QRPQLRTPFQ 60
QFSSLTHLSL HKLKLSPIKY GYQPRRNFWP ARLAARLLKL RYIILGSAVG GGYTAKKTFD 120
EWKDMIPDLS DYKWIVPDFI WEIDEYIDLE KIRKALPSSE DLASLAPDLD KITESLSLLK 180
DFFTAGPKLV SEVLEVSEAL LLLGSPGETA FRATDHGSES DKHYRKVSDK EKIDQLQEEL 240
LHTQLKYQRI LERLEKENKE LRKLVLQKDD KGIHHRKLKK SLIDMYSEVL DVLSDYDASY 300
NTQDHLPRVV VVGDQSAGKT SVLEMIAQAR IFPRGSGEMM TRSPVKVTLS EGPHHVALFK 360
DSSREFDLTK EEDLAALRHE IELRMRKNVK EGCTVSPETI SLNVKGPGLQ RMVLVDLPGV 420
INTVTSGMAP DTKETIFSIS KAYMQNPNAI ILCIQDGSVD AERSIVTDLV SQMDPHGRRT 480
IFVLTKVDLA EKNVASPSRI QQIIEGKLFP MKALGYFAVV TGKGNSSESI EAIREYEEEF 540
FQNSKLLKTS MLKAHQVTTR NLSLAVSDCF WKMVRESVEQ QADSFKATRF NLETEWKNNY 600
PRLRELDRNE LFEKAKNEIL DEVISLSQVT PKHWEEILQQ SLWERVSTHV IENIYLPAAQ 660
TMNSGTFNTT VDIKLKQWTD KQLPNKAVEV AWETLQEEFS RFMTEPKGKE HDDIFDKLKE 720
AVKEESIKRH KWNDFAEDSL RVIQHNALED RSISDKQQWD AAIYFMEEAL QGRLKDTENA 780
IENMIGPDWK KRWMYWKNRT QEQCVHNETK NELEKMLKVN DEHPAYLASD EITTVRKNLE 840
SRGVEVDPSL IKDTWHQVYR RHFLKTALNH CNLCRRGFYY YQRHFIDSEL ECNDVVLFWR 900
IQRMLAITAN TLRQQLTNTE VRRLEKNVKE VLEDFAEDGE KKVKLLTGKR VQLAEDLKKV 960
REIQEKLDAF IEALHQEK 978 
Gene Ontology
 GO:0030061; C:mitochondrial crista; IEA:Compara.
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0005741; C:mitochondrial outer membrane; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0090398; P:cellular senescence; IEA:Compara.
 GO:0006184; P:GTP catabolic process; IEA:GOC.
 GO:0007007; P:inner mitochondrial membrane organization; IEA:Compara.
 GO:0008053; P:mitochondrial fusion; IDA:MGI.
 GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IEA:Compara.
 GO:0001843; P:neural tube closure; IMP:MGI.
 GO:0007601; P:visual perception; IEA:Compara. 
Interpro
 IPR022812; Dynamin.
 IPR001401; Dynamin_GTPase.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00350; Dynamin_N 
SMART
 SM00053; DYNc 
PROSITE
  
PRINTS
 PR00195; DYNAMIN.