UniProt Accession

 NEUG_MOUSE; P60761; B2RRN7; Q3TYH4 

Genbank Protein ID

 AF230869; AK002933; AK158630; BC061102; BC138511; BC138513 

Genbank Nucleotide ID

 AAG27519.1; BAB22466.1; BAE34589.1; AAH61102.1; AAI38512.1; AAI38514.1 

Protein Name

 Neurogranin 

Protein Synonyms/Alias

 Ng; RC3; NEUG(55-78) 

Gene Name

 Nrgn 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
54	KSGECGRKGPGPGGP	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Regulates the affinity of calmodulin for calcium. Involved in synaptic plasticity and spatial learning. 

Sequence Annotation

 DOMAIN 26 47 IQ.
 DOMAIN 48 78 Collagen-like.
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 36 36 Phosphoserine; by PHK and PKC (By
 DISULFID 3 51 Or C-51 with C-4 or C-9.  

Keyword

 3D-structure; Acetylation; Calmodulin-binding; Cell junction; Cell projection; Complete proteome; Cytoplasm; Disulfide bond; Phosphoprotein; Reference proteome; Synapse. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 78 AA 

Protein Sequence

Gene Ontology

 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
 GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
 GO:0005516; F:calmodulin binding; IDA:MGI.
 GO:0007243; P:intracellular protein kinase cascade; TAS:MGI. 

Interpro

 IPR000048; IQ_motif_EF-hand-BS. 

Pfam

 PF00612; IQ 

SMART

 SM00015; IQ 

PROSITE

 PS50096; IQ 

PRINTS