CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000611
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centrin-3 
Protein Synonyms/Alias
  
Gene Name
 Cetn3 
Gene Synonyms/Alias
 Cen3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
117FDDDDSGKISLRNLRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Plays a fundamental role in microtubule-organizing center structure and function. 
Sequence Annotation
 DOMAIN 25 60 EF-hand 1.
 DOMAIN 61 96 EF-hand 2.
 DOMAIN 98 133 EF-hand 3.
 DOMAIN 134 167 EF-hand 4.  
Keyword
 Calcium; Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; Metal-binding; Mitosis; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 167 AA 
Protein Sequence
MSLALRGELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDQAIDYHEL KVAMRALGFD 60
VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL 120
RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI 167 
Gene Ontology
 GO:0005814; C:centriole; IDA:MGI.
 GO:0045111; C:intermediate filament cytoskeleton; IEA:Compara.
 GO:0005932; C:microtubule basal body; IDA:MGI.
 GO:0032391; C:photoreceptor connecting cilium; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0031683; F:G-protein beta/gamma-subunit complex binding; IDA:MGI.
 GO:0008017; F:microtubule binding; IDA:MGI.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS