CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024166
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Flotillin-2 
Protein Synonyms/Alias
 Reggie-1; REG-1 
Gene Name
 Flot2 
Gene Synonyms/Alias
 Reg1 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
211VKFMADTKIADSKRAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May play a role in axon growth and regeneration. May be involved in epidermal cell adhesion and epidermal structure and function. 
Sequence Annotation
 LIPID 4 4 S-palmitoyl cysteine; by ZDHHC5 (By
 LIPID 19 19 S-palmitoyl cysteine (By similarity).
 LIPID 20 20 S-palmitoyl cysteine; by ZDHHC5 (By  
Keyword
 Alternative splicing; Cell adhesion; Complete proteome; Endosome; Lipoprotein; Membrane; Palmitate; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 428 AA 
Protein Sequence
MGNCHTVGPN EALVVSGGCC GSDYKQYVFG GWAWAWWCIS DTQRISLEIM TLQPRCEDVE 60
TAEGVALTVT GVAQVKIMTE KELLAVACEQ FLGKNVQDIK NVVLQTLEGH LRSILGTLTV 120
EQIYQDRDQF AKLVREVAAP DVGRMGIEIL SFTIKDVYDK VDYLSSLGKT QTAVVQRDAD 180
IGVAEAERDA GIREAECKKE MLDVKFMADT KIADSKRAFE LQKSAFSEEV NIKTAEAQLA 240
YELQGAREQQ KIRQEEIEIE VVQRKKQIAV EAQEILRTDK ELIATVRRPA EAEAHRIQQI 300
AEGEKVKQVL LAQAEAEKIR KIGEAEAAVI EAMGKAEAER MKLKAEAYQK YGDAAKMALV 360
LEALPQIAAK ISAPLTKVDE IVVLSGDNSK VTSEVNRLLA ELPASVHALT GVDLSKIPLI 420
KNATGAQV 428 
Gene Ontology
 GO:0002080; C:acrosomal membrane; IEA:Compara.
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0030139; C:endocytic vesicle; ISS:UniProtKB.
 GO:0005768; C:endosome; ISS:UniProtKB.
 GO:0016600; C:flotillin complex; IDA:RGD.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. 
Interpro
 IPR001107; Band_7. 
Pfam
 PF01145; Band_7 
SMART
 SM00244; PHB 
PROSITE
  
PRINTS