UniProt Accession

 YKT6_YEAST; P36015; D6VX04 

Genbank Protein ID

 Z28196; AY558393; BK006944 

Genbank Nucleotide ID

 CAA82040.1; AAS56719.1; DAA08970.1 

Protein Name

 Synaptobrevin homolog YKT6 

Protein Synonyms/Alias

  

Gene Name

 YKT6 

Gene Synonyms/Alias

 YKL196C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
15	VFRSGGEKALELSEV	ubiquitination	[1]
123	TNDALKMKQLDTYIS	ubiquitination	[1]
131	QLDTYISKYQDPSQA	acetylation	[2]
131	QLDTYISKYQDPSQA	ubiquitination	[1]
143	SQADAIMKVQQELDE	ubiquitination	[1]
152	QQELDETKIVLHKTI	ubiquitination	[1]
168	NVLQRGEKLDNLVDK	ubiquitination	[1]
175	KLDNLVDKSESLTAS	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

  

Sequence Annotation

 DOMAIN 7 129 Longin.
 DOMAIN 140 200 v-SNARE coiled-coil homology.
 MOD_RES 158 158 Phosphothreonine.
 MOD_RES 197 197 Cysteine methyl ester (By similarity).
 LIPID 196 196 S-palmitoyl cysteine (By similarity).
 LIPID 197 197 S-farnesyl cysteine (By similarity).  

Keyword

 3D-structure; Cell membrane; Coiled coil; Complete proteome; Lipoprotein; Membrane; Methylation; Palmitate; Phosphoprotein; Prenylation; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 200 AA 

Protein Sequence

Gene Ontology

 GO:0005768; C:endosome; IDA:SGD.
 GO:0000324; C:fungal-type vacuole; IDA:SGD.
 GO:0005794; C:Golgi apparatus; IDA:SGD.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0031201; C:SNARE complex; IDA:SGD.
 GO:0016409; F:palmitoyltransferase activity; IDA:SGD.
 GO:0005484; F:SNAP receptor activity; IDA:SGD.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:SGD.
 GO:0042144; P:vacuole fusion, non-autophagic; IMP:SGD.
 GO:0006906; P:vesicle fusion; IDA:SGD. 

Interpro

 IPR011012; Longin-like_dom.
 IPR010908; Longin_dom.
 IPR001388; Synaptobrevin. 

Pfam

 PF13774; Longin
 PF00957; Synaptobrevin 

SMART

  

PROSITE

 PS50859; LONGIN
 PS00417; SYNAPTOBREVIN
 PS50892; V_SNARE 

PRINTS

 PR00219; SYNAPTOBREVN.