UniProt Accession

 ATP5S_HUMAN; Q99766; A8K1U3; D9N156; Q8WWX3; Q96F77 

Genbank Protein ID

 U79253; AY052377; AK290008; AL359397; CH471078; CH471078; BC011549 

Genbank Nucleotide ID

 AAB50202.1; AAL13058.1; BAF82697.1; EAW65718.1; EAW65722.1; AAH11549.1 

Protein Name

 ATP synthase subunit s, mitochondrial 

Protein Synonyms/Alias

 ATP synthase-coupling factor B; FB; Mitochondrial ATP synthase regulatory component factor B 

Gene Name

 ATP5S 

Gene Synonyms/Alias

 ATPW 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
99	LPTGPLDKYKIQAID	acetylation	[1]

Reference

 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861] 

Functional Description

 Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway (By similarity). 

Sequence Annotation

 REPEAT 77 102 LRR 1.
 REPEAT 103 131 LRR 2.
 REPEAT 132 156 LRR 3.
 REPEAT 157 188 LRR 4.
 REGION 1 76 N-terminal domain.
 METAL 74 74 Magnesium; via carbonyl oxygen (By
 METAL 108 108 Magnesium (By similarity).  

Keyword

 Alternative splicing; ATP synthesis; CF(0); Complete proteome; Direct protein sequencing; Hydrogen ion transport; Ion transport; Leucine-rich repeat; Magnesium; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Repeat; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 215 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; NAS:UniProtKB.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW. 

Interpro

 IPR026063; ATP_synthase_s. 

Pfam

  

SMART

  

PROSITE

 PS51450; LRR 

PRINTS