UniProt Accession

 Q66H79_RAT; Q66H79 

Genbank Protein ID

 AABR06037614; BC081980; BC091385; CH473978 

Genbank Nucleotide ID

 AAH81980.1; AAH91385.1; EDM10507.1 

Protein Name

 Protein Trim32 

Protein Synonyms/Alias

 Tripartite motif protein 32 

Gene Name

 Trim32 

Gene Synonyms/Alias

 rCG_55173 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
205	EELARSRKFFTGSLA	ubiquitination	[1]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 655 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; ISS:BHF-UCL.
 GO:0005863; C:striated muscle myosin thick filament; IEA:Compara.
 GO:0003723; F:RNA binding; IEA:Compara.
 GO:0031369; F:translation initiation factor binding; ISS:BHF-UCL.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0045444; P:fat cell differentiation; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Compara.
 GO:0045787; P:positive regulation of cell cycle; IEA:Compara.
 GO:0030307; P:positive regulation of cell growth; IEA:Compara.
 GO:0030335; P:positive regulation of cell migration; IEA:Compara.
 GO:0050769; P:positive regulation of neurogenesis; IEA:Compara.
 GO:0045666; P:positive regulation of neuron differentiation; IEA:Compara.
 GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Compara.
 GO:0045732; P:positive regulation of protein catabolic process; ISS:BHF-UCL.
 GO:0045862; P:positive regulation of proteolysis; IEA:Compara.
 GO:0000209; P:protein polyubiquitination; IEA:Compara.
 GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Compara.
 GO:0034612; P:response to tumor necrosis factor; IEA:Compara.
 GO:0009411; P:response to UV; IEA:Compara. 

Interpro

 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR001258; NHL_repeat.
 IPR013017; NHL_repeat_subgr.
 IPR027370; zf-RING_LisH.
 IPR000315; Znf_B-box.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 

Pfam

 PF01436; NHL
 PF13445; zf-RING_LisH 

SMART

 SM00336; BBOX
 SM00184; RING 

PROSITE

 PS51125; NHL
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 

PRINTS