CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003738
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S8-A 
Protein Synonyms/Alias
 RP19; S14; YS9 
Gene Name
 RPS8A 
Gene Synonyms/Alias
 RPS14A; YBL072C; YBL06.05; YBL0613 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
26AQFRKKRKFELGRQPacetylation[1]
37GRQPANTKIGAKRIHubiquitination[2]
74WASEGISKKTRIAGVacetylation[1]
74WASEGISKKTRIAGVubiquitination[2]
98VRTNTLTKAAIVQIDubiquitination[2]
128LGKKKNVKEEETVAKacetylation[1]
128LGKKKNVKEEETVAKubiquitination[2]
135KEEETVAKSKNAERKubiquitination[3]
151AARAASAKIESSVESubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
  
Sequence Annotation
 MOD_RES 62 62 Phosphothreonine.
 MOD_RES 66 66 Phosphoserine.
 MOD_RES 69 69 Phosphoserine.
 MOD_RES 73 73 Phosphoserine.
 MOD_RES 86 86 Phosphoserine.
 MOD_RES 107 107 Phosphothreonine.
 MOD_RES 154 154 Phosphoserine.
 MOD_RES 155 155 Phosphoserine.
 MOD_RES 158 158 Phosphoserine.
 MOD_RES 161 161 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 200 AA 
Protein Sequence
MGISRDSRHK RSATGAKRAQ FRKKRKFELG RQPANTKIGA KRIHSVRTRG GNKKYRALRI 60
ETGNFSWASE GISKKTRIAG VVYHPSNNEL VRTNTLTKAA IVQIDATPFR QWFEAHYGQT 120
LGKKKNVKEE ETVAKSKNAE RKWAARAASA KIESSVESQF SAGRLYACIS SRPGQSGRCD 180
GYILEGEELA FYLRRLTAKK 200 
Gene Ontology
 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IC:SGD.
 GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IGI:SGD.
 GO:0006414; P:translational elongation; IBA:RefGenome. 
Interpro
 IPR001047; Ribosomal_S8e.
 IPR022309; Ribosomal_S8e/biogenesis_NSA2.
 IPR018283; Ribosomal_S8e_CS. 
Pfam
 PF01201; Ribosomal_S8e 
SMART
  
PROSITE
 PS01193; RIBOSOMAL_S8E 
PRINTS