CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028118
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hpr1 
Protein Synonyms/Alias
 Hpr1 protein; LD43883p 
Gene Name
 Hpr1 
Gene Synonyms/Alias
 hpr1; CG2031; Dmel_CG2031 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
310KANHFFAKFLTNPKLacetylation[1]
446RDASRSGKFYLGNDNacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 701 AA 
Protein Sequence
MSTAVEVANT APEKLANYFA LQSAFEKALE LAITDGKVEL LVKEYNRFPA NTEHDKRLPM 60
DHAFRVLLMK RLDEDVSRIG ELVRLSVEAT RAEIVSNTIP VVLLIDTFDV VTLDKCQKIF 120
QFVEDMVEVW KEEIFFSSCK NNILRMCNDL LRRLSRTQNT VFCGRIQLFL SKFFPFSERS 180
GLNIVSEFNL DNFTEYGLDS KDHDESDNKE LEDTAEDIPL KIDYDLYCKF WSLQDFFRNP 240
NQCYNKPQWK MFQMHADNIL QSFSSFKLED VRQSSNENAS GTDQAMDVDE EAVDTTAVSS 300
VIKANHFFAK FLTNPKLLAL QLSDANFRRA VLVQFLILFQ YLQVSVKFKS DTQTLTADQA 360
DFIKETESRV YKLLEETPPY GKRFSRTVYH MLAREEMWNN WKNEGCKEFK KPEEPTLSEE 420
DSKPTPNKRP RRPLGDALRD ASRSGKFYLG NDNLTRLWNY SPDNLQACKS EQRNFLPLLE 480
TYLETPHEKV DPAFEWRALR LLARQTPHFF TSLSQPSSKI SDYLEQVRKR LIRDKEPKPA 540
ALLSNNSSEN NFGLSVNNVH TEGEQDATVA LQDGEPEQDL EVEDNEPVVE EVDEVPAHEK 600
PLMVTKEHIE EVAPLIGEPW MKVGKKIGFT NDELLFFQME HPTANVACVK MLTNWISDDD 660
DATLENWAYM LEGLEMNKAA EAVKAIIERE KSGSTAAFCL R 701 
Gene Ontology
 GO:0000347; C:THO complex; IDA:FlyBase.
 GO:0031990; P:mRNA export from nucleus in response to heat stress; IMP:FlyBase.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR011029; DEATH-like_dom.
 IPR000488; Death_domain.
 IPR021861; THO_THOC1. 
Pfam
 PF00531; Death
 PF11957; efThoc1 
SMART
  
PROSITE
 PS50017; DEATH_DOMAIN 
PRINTS