CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033075
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Signal transducer and activator of transcription 5B 
Protein Synonyms/Alias
  
Gene Name
 STAT5B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71LVQELQKKAEHQVGEubiquitination[1]
140LADAMSQKHLQINQTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 156 AA 
Protein Sequence
MAVWIQAQQL QGEALHQMQA LYGQHFPIEV RHYLSQWIES QAWDSVDLDN PQENIKATQL 60
LEGLVQELQK KAEHQVGEDG FLLKIKLGHY ATQLQNTYDR CPMELVRCIR HILYNEQRLV 120
REANNGSSPA GSLADAMSQK HLQINQTFEE LRLVTQ 156 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003690; F:double-stranded DNA binding; IEA:Compara.
 GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0004871; F:signal transducer activity; IEA:Compara.
 GO:0006103; P:2-oxoglutarate metabolic process; IEA:Compara.
 GO:0006953; P:acute-phase response; IEA:Compara.
 GO:0000255; P:allantoin metabolic process; IEA:Compara.
 GO:0006101; P:citrate metabolic process; IEA:Compara.
 GO:0006600; P:creatine metabolic process; IEA:Compara.
 GO:0046449; P:creatinine metabolic process; IEA:Compara.
 GO:0019221; P:cytokine-mediated signaling pathway; IEA:Compara.
 GO:0046543; P:development of secondary female sexual characteristics; IEA:Compara.
 GO:0046544; P:development of secondary male sexual characteristics; IEA:Compara.
 GO:0006631; P:fatty acid metabolic process; IEA:Compara.
 GO:0007565; P:female pregnancy; IEA:Compara.
 GO:0006549; P:isoleucine metabolic process; IEA:Compara.
 GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; IEA:Compara.
 GO:0007595; P:lactation; IEA:Compara.
 GO:0019915; P:lipid storage; IEA:Compara.
 GO:0001889; P:liver development; IEA:Compara.
 GO:0001553; P:luteinization; IEA:Compara.
 GO:0001779; P:natural killer cell differentiation; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0045647; P:negative regulation of erythrocyte differentiation; IEA:Compara.
 GO:0006107; P:oxaloacetate metabolic process; IEA:Compara.
 GO:0048541; P:Peyer's patch development; IEA:Compara.
 GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Compara.
 GO:0045579; P:positive regulation of B cell differentiation; IEA:Compara.
 GO:0051272; P:positive regulation of cellular component movement; IEA:Compara.
 GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Compara.
 GO:0050729; P:positive regulation of inflammatory response; IEA:Compara.
 GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Compara.
 GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Compara.
 GO:0040018; P:positive regulation of multicellular organism growth; IEA:Compara.
 GO:0032825; P:positive regulation of natural killer cell differentiation; IEA:Compara.
 GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Compara.
 GO:0032819; P:positive regulation of natural killer cell proliferation; IEA:Compara.
 GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0042448; P:progesterone metabolic process; IEA:Compara.
 GO:0030155; P:regulation of cell adhesion; IEA:Compara.
 GO:0030856; P:regulation of epithelial cell differentiation; IEA:Compara.
 GO:0019218; P:regulation of steroid metabolic process; IEA:Compara.
 GO:0045471; P:response to ethanol; IEA:Compara.
 GO:0001666; P:response to hypoxia; IEA:Compara.
 GO:0070672; P:response to interleukin-15; IEA:Compara.
 GO:0070669; P:response to interleukin-2; IEA:Compara.
 GO:0070670; P:response to interleukin-4; IEA:Compara.
 GO:0032496; P:response to lipopolysaccharide; IEA:Compara.
 GO:0006105; P:succinate metabolic process; IEA:Compara.
 GO:0033077; P:T cell differentiation in thymus; IEA:Compara.
 GO:0043029; P:T cell homeostasis; IEA:Compara.
 GO:0019530; P:taurine metabolic process; IEA:Compara.
 GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006573; P:valine metabolic process; IEA:Compara. 
Interpro
 IPR001217; STAT_TF_core.
 IPR013799; STAT_TF_prot_interaction. 
Pfam
 PF02865; STAT_int 
SMART
 SM00964; STAT_int 
PROSITE
  
PRINTS