CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035427
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Atp6v1a 
Protein Synonyms/Alias
 RCG52629 
Gene Name
 Atp6v1a 
Gene Synonyms/Alias
 rCG_52629 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
5***MDFSKLPKIRDEubiquitination[1]
132SALSRDIKWEFIPSKacetylation[2]
139KWEFIPSKNLRVGSHacetylation[2]
139KWEFIPSKNLRVGSHubiquitination[1]
163VNENSLIKHKIMLPPacetylation[2]
165ENSLIKHKIMLPPRSacetylation[2]
220QVRPVTEKLPANHPLacetylation[2]
467ALDEYYDKHFTEFVPacetylation[2]
513KITLEVAKLIKDDFLubiquitination[1]
516LEVAKLIKDDFLQQNacetylation[2]
516LEVAKLIKDDFLQQNubiquitination[1]
580HMGEILYKLSSMKFKacetylation[2]
587KLSSMKFKDPVKDGEacetylation[2]
591MKFKDPVKDGEAKIKacetylation[2]
596PVKDGEAKIKADYAQubiquitination[1]
598KDGEAKIKADYAQLLacetylation[2]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrogen ion transport; Ion transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 617 AA 
Protein Sequence
MDFSKLPKIR DEDKESTFGY VHGVSGPVVT ACDMAGAAMY ELVRVGHSEL VGEIIRLEGD 60
MATIQVYEET SGVSVGDPVL RTGKPLSVEL GPGIMGAIFD GIQRPLSDIS SQTQSIYIPR 120
GVNVSALSRD IKWEFIPSKN LRVGSHITGG DIYGIVNENS LIKHKIMLPP RSRGSVTYIA 180
PPGNYDASDV VLELEFEGVK EKLSMVQVWP VRQVRPVTEK LPANHPLLTG QRVLDALFPC 240
VQGGTTAIPG AFGCGKTVIS QSLSKYSNSD VIIYVGCGER GNEMSEVLRD FPELTMEVDG 300
KVESIMKRTA LVANTSNMPV AAREASIYTG ITLSEYFRDM GYHVSMMADS TSRWAEALRE 360
ISGRLAEMPA DSGYPAYLGA RLASFYERAG RVKCLGNPER EGSVSIVGAV SPPGGDFSDP 420
VTSATLGIVQ VFWGLDKKLA QRKHFPSVNW LISYSKYMRA LDEYYDKHFT EFVPLRTKAK 480
EILQEEEDLA EIVQLVGKAS LAETDKITLE VAKLIKDDFL QQNGYTPYDR FCPFYKTVGM 540
LSNMISFYDM ARRAVETTAQ SDNKITWSII REHMGEILYK LSSMKFKDPV KDGEAKIKAD 600
YAQLLEDMQN AFRSLED 617 
Gene Ontology
 GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro. 
Interpro
 IPR020003; ATPase_a/bsu_AS.
 IPR004100; ATPase_a/bsu_N.
 IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C.
 IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
 IPR024034; ATPase_F1_bsu/V1_C.
 IPR005725; ATPase_V1-cplx_asu.
 IPR027417; P-loop_NTPase.
 IPR022878; V-ATPase_su_A/alpha. 
Pfam
 PF00006; ATP-synt_ab
 PF00306; ATP-synt_ab_C
 PF02874; ATP-synt_ab_N 
SMART
  
PROSITE
 PS00152; ATPASE_ALPHA_BETA 
PRINTS