CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017535
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Activator of 90 kDa heat shock protein ATPase homolog 2 
Protein Synonyms/Alias
  
Gene Name
 Ahsa2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
37RDATIWSKGKLRELLubiquitination[1]
156GEYLKALKTEFTTGMubiquitination[1]
185QRKLNENKLQASPVAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Co-chaperone that stimulates HSP90 ATPase activity (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Chaperone; Complete proteome; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 331 AA 
Protein Sequence
MAKWGQGDPR WIVEEREDGT NVNNWHWTER DATIWSKGKL RELLVGIAME NEAGRCEISE 60
LKQVEGEASC NSRKGKLIFF YEWNIKLAWK GTVKESGAKH KGLIEIPSLS EENEINDTEV 120
NVSKKKGDGE ILKDLMRTTG TAKVREALGE YLKALKTEFT TGMILPTKAV ATQELTLQRK 180
LNENKLQASP VALGVRIPTV ALHLTELFDT TVEQLYSIFT VKELVQKFSK SPAVLEAERG 240
GKFQMFDGNI SGEYVELVTN RKIIMKWRCR NWPEEHYATV ELNFVPAPGQ TELQLDCKGV 300
PVCKEENMKF CWQKQHFEEI KGLLELTAQN A 331 
Gene Ontology
 GO:0001671; F:ATPase activator activity; IEA:InterPro.
 GO:0032781; P:positive regulation of ATPase activity; IEA:GOC.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR013538; Activator_of_Hsp90_ATPase.
 IPR015310; AHSA1_N.
 IPR023393; START-like_dom. 
Pfam
 PF09229; Aha1_N
 PF08327; AHSA1 
SMART
 SM01000; Aha1_N 
PROSITE
  
PRINTS