CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039022
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Microtubule-associated protein 1B 
Protein Synonyms/Alias
  
Gene Name
 Map1b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
98SPEVPGQKILHHRSDacetylation[1]
429MYVLNPVKSSKEMQYubiquitination[2]
506LEGLEKLKHLDFLKQacetylation[1]
519KQPLATQKDLTGQVSubiquitination[2]
531QVSTPPVKQVKLKQRubiquitination[2]
700ELKKEVKKETPLKDAacetylation[1]
837TKDFEELKAEEIDVAubiquitination[2]
848IDVAKDIKPQLELIEubiquitination[2]
861IEDEEKLKETEPGEAubiquitination[2]
873GEAYVIQKETEVSKGubiquitination[2]
1348LPTEVTEKPQAVPVSacetylation[1]
1762YASLASEKVQSLEGEacetylation[1]
1770VQSLEGEKLSPKSDIacetylation[1]
1955YSYEISEKTTRTPEVubiquitination[2]
1969VSGYTYEKTERSRRLacetylation[1]
1969VSGYTYEKTERSRRLubiquitination[2]
2023YSYETTTKTTRSPDTubiquitination[2]
2043ETMEKITKTPQASTYubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2461 AA 
Protein Sequence
MATVVVEATE PEPSGSIGNP AATTSPSLSH RFLDSKFYLL VVVGETVTEE HLRRAIGNIE 60
LGIRSWDTNL IECNLDQELK LFVSRHSARF SPEVPGQKIL HHRSDVLETV VLINPSDEAV 120
STEVRLMITD AARHKLLVLT GQCFENTGEL ILQSGSFSFQ NFIEIFTDQE IGELLSTTHP 180
ANKASLTLFC PEEGDWKNSN LDRHNLQDFI NIKLNSASIL PEMEGLSEFT EYLSESVEVP 240
SPFDILEPPT SGGFLKLSKP CCYIFPGGRG DSALFAVNGF NMLINGGSER KSCFWKLIRH 300
LDRVDSILLT HIGDDNLPGI NSMLQRKIAE LEEERSQGST SNSDWMKNLI SPDLGVVFLN 360
VPENLKNPEP NIKMKRSTEE ACFTLQYLNK LSMKPEPLFR SVGNAIEPVI LFQKMGVGKL 420
EMYVLNPVKS SKEMQYFMQQ WTGTNKDKAE LILPNGQEVD IPISYLTSVS SLIVWHPANP 480
AEKIIRVLFP GNSTQYNILE GLEKLKHLDF LKQPLATQKD LTGQVSTPPV KQVKLKQRAD 540
SRESLKPATK PLSSKSVRKE SKEEAPEATK ASQVEKTPKV ESKEKVIVKK DKPGKVESKP 600
SVTEKEVPSK EEQSPVKAEV AEKAATESKP KVTKDKVVKK EIKTKPEEKK EEKPKKEVAK 660
KEDKTPLKKD EKPKKEEAKK EIKKEIKKEE KKELKKEVKK ETPLKDAKKE VKKDEKKEVK 720
KEEKEPKKEI KKISKDIKKS TPLSDTKKPA ALKPKVAKKE EPTKKEPIAA GKLKDKGKVK 780
VIKKEGKTTE AAATAVGTAA VAAAAGVAAS GPAKELEAER SLMSSPEDLT KDFEELKAEE 840
IDVAKDIKPQ LELIEDEEKL KETEPGEAYV IQKETEVSKG SAESPDEGIT TTEGEGECEQ 900
TPEELEPVEK QGVDDIEKFE DEGAGFEESS EAGDYEEKAE TEEAEEPEED GEDNVSGSAS 960
KHSPTEDEEI AKAEADVHIK EKRESVASGD DRAEEDMDEA LEKGEAEQSE EEGEEEEDKA 1020
EDAREEDHEP DKTEAEDYVM AVVDKAAEAG VTEDQYGFLG TPAKQPGVQS PSREPASSIH 1080
DETLPGGSES EATASDEENR EDQPEEFTAT SGYTQSTIEI SSEPTPMDEM STPRDVMSDE 1140
TNNEETESPS QEFVNITKYE SSLYSQEYSK PVVASFNGLS DGSKTDATDG RDYNASASTI 1200
SPPSSMEEDK FSKSALRDAY RPEETDVKTG AELDIKDVSD ERLSPAKSPS LSPSPPSPIE 1260
KTPLGERSVN FSLTPNEIKA SAEGEATAVV SPGVTQAVVE EHCASPEEKT LEVVSPSQSV 1320
TGSAGHTPYY QSPTDEKSSH LPTEVTEKPQ AVPVSFEFTE AKDENERSSI SPMDEPVPDS 1380
ESPIEKVLSP LRSPPLIGSE SAYEDFLSAD DKALGRRSES PFEGKNGKQG FSDKESPVSD 1440
LTSDLYQDKQ EEKSAGFIPI KEDFSPEKKA SDAEIMSSQS ALALDERKLG GDGSPTQVDV 1500
SQFGSFKEDT KMSISEGTVS DKSATPVDEG VAEDTYSHME GVASVSTASV ATSSFPEPTT 1560
DDVSPSLHAE VGSPHSTEVD DSLSVSVVQT PTTFQETEMS PSKEECPRPM SISPPDFSPK 1620
TAKSRTPVQD HRSEQSSMSI EFGQESPEHS LAMDFSRQSP DHPTVGAGML HITENGPTEV 1680
DYSPSDIQDS SLSHKIPPTE EPSYTQDNDL SELISVSQVE ASPSTSSAHT PSQIASPLQE 1740
DTLSDVVPPR DMSLYASLAS EKVQSLEGEK LSPKSDISPL TPRESSPTYS PGFSDSTSGA 1800
KESTAAYQTS SSPPIDAAAA EPYGFRSSML FDTMQHHLAL SRDLTTSSVE KDNGGKTPGD 1860
FNYAYQKPES TTESPDEEDY DYESHEKTIQ AHDVGGYYYE KTERTIKSPC DSGYSYETIE 1920
KTTKTPEDGG YSCEITEKTT RTPEEGGYSY EISEKTTRTP EVSGYTYEKT ERSRRLLDDI 1980
SNGYDDTEDG GHTLGDCSYS YETTEKITSF PESESYSYET TTKTTRSPDT SAYCYETMEK 2040
ITKTPQASTY SYETSDRCYT PERKSPSEAR QDVDLCLVSS CEFKHPKTEL SPSFINPNPL 2100
EWFAGEEPTE ESEKPLTQSG GAPPPSGGKQ QGRQCDETPP TSVSESAPSQ TDSDVPPETE 2160
ECPSITADAN IDSEDESETI PTDKTVTYKH MDPPPAPMQD RSPSPRHPDV SMVDPEALAI 2220
EQNLGKALKK DLKEKAKTKK PGTKTKSSSP VKKGDGKSKP SAASPKPGAL KESSDKVSRV 2280
ASPKKKESVE KAMKTTTTPE VKATRGEEKD KETKNAANAS ASKSVKTATA GPGTTKTAKS 2340
STVPPGLPVY LDLCYIPNHS NSKNVDVEFF KRVRSSYYVV SGNDPAAEEP SRAVLDALLE 2400
GKAQWGSNMQ VTLIPTHDSE VMREWYQETH EKQQDLNIMV LASSSTVVMQ DESFPACKIE 2460
L 2461 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005874; C:microtubule; IEA:InterPro.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0007409; P:axonogenesis; IEA:Compara.
 GO:0016358; P:dendrite development; IEA:Compara.
 GO:0061162; P:establishment of monopolar cell polarity; IEA:Compara.
 GO:0001578; P:microtubule bundle formation; IEA:Compara.
 GO:0047497; P:mitochondrion transport along microtubule; IEA:Compara.
 GO:0032387; P:negative regulation of intracellular transport; IEA:Compara.
 GO:0045773; P:positive regulation of axon extension; IEA:Compara. 
Interpro
 IPR001279; Beta-lactamas-like.
 IPR026074; MAP1.
 IPR027321; MAP1B.
 IPR000102; MAP1B_neuraxin. 
Pfam
 PF00414; MAP1B_neuraxin 
SMART
  
PROSITE
 PS00230; MAP1B_NEURAXIN 
PRINTS