UniProt Accession

 YNIC_ECOLI; P77247; P78167 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74797.1; BAA15508.1 

Protein Name

 2-deoxyglucose-6-phosphate phosphatase 

Protein Synonyms/Alias

 Sugar phosphatase 

Gene Name

 yniC 

Gene Synonyms/Alias

 b1727; JW1716 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
143	DALASAEKLPYSKPH	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Catalyzes strongly the dephosphorylation of 2- deoxyglucose 6-phosphate (2dGlu6P) and slightly the dephosphorylation of mannose 6-phosphate (Man6P), 2-deoxyribose-5- phosphate (2dRib5P), ribose-5-phosphate (Rib5P) and glucose-6- phosphate (Glu6P). 

Sequence Annotation

 REGION 13 15 Substrate.
 REGION 115 116 Substrate.
 ACT_SITE 13 13 Nucleophile.
 METAL 13 13 Magnesium (By similarity).
 METAL 15 15 Magnesium (By similarity).
 METAL 173 173 Magnesium (By similarity).
 BINDING 148 148 Substrate.  

Keyword

 3D-structure; Complete proteome; Hydrolase; Magnesium; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 222 AA 

Protein Sequence

Gene Ontology

 GO:0003850; F:2-deoxyglucose-6-phosphatase activity; IDA:EcoliWiki.
 GO:0004346; F:glucose-6-phosphatase activity; IDA:EcoliWiki.
 GO:0000287; F:magnesium ion binding; IDA:UniProtKB. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006402; HAD-SF_hydro_IA_v3.
 IPR005833; Haloacid_DH/epoxide_hydro.
 IPR023198; PGP_dom2. 

Pfam

 PF00702; Hydrolase 

SMART

  

PROSITE

  

PRINTS

 PR00413; HADHALOGNASE.