| Tag | Content |
|---|
| CPLM ID | CPLM-016765 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glucose 1,6-bisphosphate synthase |
Protein Synonyms/Alias | Phosphoglucomutase-2-like 1 |
Gene Name | Pgm2l1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 394 | TVSSKILKAIALKEG | ubiquitination | [1] | | 476 | TLMEQLTKVYEIYGY | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1- phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1- phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5- bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities (By similarity). |
Sequence Annotation | ACT_SITE 175 175 Phosphoserine intermediate (By
MOD_RES 175 175 Phosphoserine (By similarity). |
Keyword | Carbohydrate metabolism; Complete proteome; Direct protein sequencing; Glucose metabolism; Isomerase; Phosphoprotein; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 621 AA |
Protein Sequence | MAENADDDLN SNLLHAPYLT GDPQLDTAIG QWLRWDKNPK TKEQIENLLR NGMNKELRDR 60
LCCRMTFGTA GLRSAMGAGF CYINDLTVIQ STQGMYKYLE RCFSDFKQRG FVVGYDTRGQ 120
VTSSCSSQRL AKLTAAVLLA KDIPVYLFSR YVPTPFVPYA VQELKAVAGV MITASHNRKE 180
DNGYKVYWET GAQITSPHDK EILKCIEECV EPWNDSWNDN LVDTSPLKKD PLQDICKKYM 240
EDLKKICFYR DLNSKTTLKF VHTSFHGVGH DYVQLAFQVF GFKPPIPVPE QKDPDPDFST 300
VKCPNPEEGE SVLELSLRLA EKENARIVLA TDPDADRLAV AELQENGRWK VFTGNELAAL 360
FGWWMFDCWK KNKPNADVKN VYMLATTVSS KILKAIALKE GFHFEETLPG FKWIGSRIKD 420
LLGNGKEVLF AFEESIGFLC GTSVLDKDGV SAAAVVAEMA SFLDTRKVTL MEQLTKVYEI 480
YGYHMSKTSY FLCYDPPTIK TIFERIRNFE SPKEYPKFCG AFAILHVRDI TTGYDSSQPN 540
KKSVLPVSKN SQMITFTFQN GCVATLRTSG TEPKIKYYAE MCASPGQSDT TFLEEELKKL 600
IDALIENFLE PSKNALVWRS V 621 |
Gene Ontology | GO:0005829; C:cytosol; IBA:RefGenome. GO:0047933; F:glucose-1,6-bisphosphate synthase activity; IEA:EC. GO:0004614; F:phosphoglucomutase activity; IBA:RefGenome. GO:0016052; P:carbohydrate catabolic process; IBA:RefGenome. GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |